R/O - Arthropathies and septic arthritis Flashcards Preview

Year 2 Specialty Medicine > R/O - Arthropathies and septic arthritis > Flashcards

Flashcards in R/O - Arthropathies and septic arthritis Deck (23):
1

what is the triad for gonococcal arthritis?

1. tenosynovitis
2. vesiculopustular skin lesions
3. polyarthralgia

2

is gonococcal monoarthritis purulent or non-purulent?

purulent

3

what is the treatment for gram positive cocci septic arthritis?

vancomycin

4

what is the treatment for gram negative bacilli septic arthritis?

3rd gen ceph

5

what medications can induce gouty monoarthritis?

- ASA (low dose)
- hydrochlorothiazide

6

what is the diagnosis for gout?

- synovial fluid analysis
- intracellular monosodium urate
- crystals are NEGATIVELY birifringent
- WBC 10k - 100k

parallel and yellow - gout (negative)

7

what does plain radiography show in gout?

- subcortical bone cysts
- bone erosions with overhanging edges

8

what is the primary pathophysiology mechanism of gout?

impaired excretion

9

what is the goal uric acid level for prevention of recurrent gout?

6 mg / dL (solubility level)

10

where is febuxostat cleared?

liver

11

what drugs are used for prophylaxis during initiation of antihyperuricemic therapy?

- colchicine
- NSAIDs

12

acute attacks of calcium pyrophosphate crystal deposition disease (CPPD) occur in _____ (men / women), and osteoarthritis with chondrocalcinosis occurs in _________ (men / women)

- men
- women

13

what are the clinical manifestations of CPPD?

- spine involvement
- crowded dens syndrome: recurrent fever, elevated CRP and ESR, neck and shoulder girdle pain and stiffness

14

how is CPPD diagnosed?

- synovial fluid
- positively birifringent CPP crystals
- WBC 15k - 30k

15

- rhomboid crystals
- pale blue when aligned with axis of compensator

CPPD

16

what is the treatment of acute pseudogout?

- oligoarticular: steroids
- polyarticular: NSAIDs, colchicine, oral steroids, ACTH

17

definition: spondyloarthropathies

inflammation of axial joints, asymmetrical oligoarthritis, dactylitis, and enthesitis

18

spondyloarthropathies are often associated with manifestations in what other parts of the body?

- eye and bowel inflammation
- preceding infection
- positive familiy history
- HLA B27

19

dactylitis - sausage finger is seen in what condition?

spondyloarthropathies

20

what are the clinical manifestations of spondyloarthropathies?

- skeletal: low back pain (inflammatory), peripheral arthritis, enthesopathy, dactylitis

- non-skeletal: conjunctivitis, anterior uveitis, inflammatory bowel disease, psoriasis

21

what is the lab eval for spondyloarthropathies?

- HLA B27
- ESR
- CRP

22

what do radiographs show for spondyloarthropathies?

- SI joints
- hands
- feet

23

what are the pharm treatments for spondyloarthropathies?

- NSAIDs
- analgesics
- DMARDs
- biologics