R/O - Introduction to arthritis Flashcards

1
Q

pubic symphysis, SI, and spine are what type of joints?

A

amphiarthroses

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2
Q

what are the red flag for joint exam?

A
  • acute monoarticular arthritis with inflammation
  • cranial symptoms in elderly patients with muscle pain
  • morning stiffness lasting over an hour in patients with back pain
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3
Q

what are the 3 reasons for lab testing in arthritis workup?

A
  • screening
  • confirming a diagnosis
  • monitoring treatment
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4
Q

what do acute phase reactants monitor?

A

intensity of inflammation

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5
Q

which changes faster - ESR or CRP?

A

CRP

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6
Q

rheumatoid factor is an antibody to the ____ portion of immunoglobulin ____

A
  • Fc

- IgG

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7
Q

do RF levels correlate with disease activity?

A

NO

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8
Q

anti-CCP antibodies are useful in what situation?

A

RF-negative patients with RA

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9
Q

can CCP antibodies be used as a screening test?

A

NO

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10
Q

what is the screening test of choice for autoimmune rheumatic disease?

A

ANA antibodies

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11
Q

a centromere pattern of ANA antibodies suggests what condition?

A

CREST

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12
Q

nucleolar pattern of ANA antibodies suggests what condition?

A

systemic scleroderma

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13
Q

anti double stranded DNA antibodies are specific to what condition?

A

SLE

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14
Q

anti-Jo1 antibodies are specific to ___________

A

polymyositis

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15
Q

anti-centromere antibodies are specific to __________

A

limited scleroderma - CREST

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16
Q

anti-U1 RNP antibodies are specific to _____________

A

primarily MCTD

17
Q

do antinuclear antibodies correlate with disease activity?

A

no

18
Q

what analysis is mandatory for acute monoarthritis?

A

synovial fluid analysis