Derm - Nodules and discharging sinuses Flashcards

1
Q

What is a discharging sinus?

A

An intense inflammatory response to infectious agents or foreign material
Leads to formation fo a tract between the epidermis surface and deeper tissues
eg. a cat bite abcess

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2
Q

How do you investigate nodules?

A

Cytology from fine needle aspirate

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3
Q

How do you investigate infectious nodules associated with discharging sinus tracts?

A

DIff quik gram stain exudate

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4
Q

How do you investigate superficial lesions extending into the dermis?

A

Punch biopsy
Histopathology
Culture

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5
Q

How do you investigate nodules extending into the hypodermis?

A

Partial excision biopsy using a scalpel

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6
Q

When should you use haematology and biochemistry to investigate skin conditions?

A

Extensive skin disease
Signs of systemic disease
Old

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7
Q

What are some bacterial causes of nodules?

A

Staphylococci
Mycobacteria

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8
Q

What are some fungal causes of nodules?

A

Dermatophytosis
Eumycotic mycetomas
Deep fungal infections

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9
Q

What can cause feline tuberculosis?

A

Commercial raw food diet

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10
Q

What are cutaneous signs of feline tuberculosis?

A

Nodular ulcerated lesions
Subcut tissue/joints/bone
Regional lymphadenopathy

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11
Q

What causes feline leprosy?

A

3 mycobacterial species
Caught from bites from wildlife eg. rodents

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12
Q

When is mycobacteria infection in cats notifiable?

A

In dead non bovine species or when culture is positive in a live cat
Contact APHA

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13
Q

What is sterile granuloma and pyogranuloma syndrome (SGPS)?

A

When an inflammatory infiltrate causes pyogranulomatous lesions in the absence of infection

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14
Q

Where does sterile granuloma and pyogranuloma syndrome (SGPS) affect?

A

Varied lesion affecting ocular tissues, nasal tissues and head

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15
Q

What are some differential diagnoses of sterile granuloma and pyogranuloma syndrome (SGPS)?

A

Neoplasia
Granulomatous reactions to foreign bodies etc.
Panniculitis

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16
Q

How can you manage sterile granuloma and pyogranuloma syndrome (SGPS)?

A

Reduce trigger factors - treat infections etc.
High dose corticosteroids - pred
Tetracycline and nicotinamide

17
Q

What are some examples of epidermal tumours?

A

Basal cell carcinoma - cat
Papilloma - dog
Squamous cell carcinome - cat

18
Q

What are some examples of hair follicle tumours?

A

Follicle cyst
Infundibular keratinising acanthoma

19
Q

What are some examples of sebaceous gland tumours?

A

Nodular sebaceous hyperplasia
Perianal gland carcinoma
Sebaceous adenoma

20
Q

What are some examples of nailbed tumours?

A

Squamous papilloma
Keratoacanthoma
Basal cell carcinoma
Metastatic pulmonary carcinoma

21
Q

What tumour is accompanied by GI signs?

A

Mast cell tumours

22
Q

What tumour is accompanied by polydipsia?

A

Lymphoma - hypercalcaemia

23
Q

Where are cutaneous T cell lymphomas found?

A

In the epithelium or in the dermis - epitheliotropic or non-epitheliotropic

24
Q

What are some examples of cutaneous T cell lymphomas?

A

Mycosis fungoides, Sezarys syndrome

25
Q

How does cutaneous T cell lymphoma present?

A

Generalised erythema, scaling and pruritus
Plaques and nodules
Loss of pigment

26
Q

How do you treat cutaneous T cell lymphoma?

A

Palliative
High dose prednisolone
Retinoids
Chemotherapy