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Flashcards in dysfunction of the male system Deck (18):
1

what are the stages of male genitalia maturation

stage one: nothing
2: testicular enlargement, start of pubic hair
3: penal enlargment, more pubic hair
4: further enlargment and darkening of pubic hair
5: adult genital appearance

2

what is the first sign of male puberty

growth of testes caused by seminiferous tubular enlargement (fsh)

3

at what stage does sperm production start

between 2 and 3

4

what is the average age of male puberty

14

5

when are the hypothalamus and pituritary gland connected

20 weeks gestastion

6

what does FSH do during puberty

stimulates enlargement of seminiferous tubules and spermatogenesis

7

what do the Leydig cells produce

testosterone, androstenedione, dihydrotestosterone, oestrodiol

8

what protein binds to testosterone

testosterone binding globulin

9

what cell produces inhibin

sertoli- negative feedback on FSH

10

what is delayed puberty

after 95% of other children have entered puberty

11

what can cause a temporary delay in puberty

familial
chronic illness
malnutrition
hormonal disturbance

12

what are the types of hypogonadotrophic hypogonadism

Kallman's syndrome + anosmia
hypopituritsm (tumour/ trauma)

13

what are the types of hypergonadotrophic hypogonidism

klinefelter's (xxy)
anorchia
orchiditis (mumps)
radiation/ chemo
castration

14

what is Kallmann's

failure of hypothalamic neurones to migrate into the hypothalamus

15

what is anorchia

no testes

16

what are the disadvantages of treating late puberty

early fusion of epiphyses

17

a boy presents with late puberty, headache and diabetes insipidus. what do you suspect?

pituritary tumour

18

what are the symptoms of hypogonadism

sexual dysfunction
fatigue
depression
osteoporosis
low muscle mass and strength
low hair