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Flashcards in loop of Henle Deck (19):
1

what parts of the nephron are in the medulla

vasa recta
loop of henle
collecting duct

2

what is the function of ADH

allows the distal tubule and collecting ducts to become permeable to water and so reabsorbed

3

how are ions absorbed across the thin ascending loop of Henle

passive absorption

4

how are ions reabsorbed in the thick ascending loop

Na- active transport
cotransport of postassium, chloride and other ions

5

what is the renal papilla

where the renal pyramids in the medulla enter into the minor calyx

6

what is normal osmolarity of the ECF

300 mOm/L

7

how does ecf change in the kidney

it is reduced to 100 mOmL in the dct

8

how concentrated can urine be

1200 mosm/l. This is the same concentration as the renal medulla.

9

what is the difference between the thick and thin ascending loops

passive absorption- thin
active transport of sodium and co transport of K and Cl- thick

10

what is the descending loop impermeable to

salt

11

what is the ascending loop impermeable to

water

12

what is the purpose of the loop of henle

counter current multiplier that generates a concentration gradient

13

what is the purpose of the thick ascending loop

establishes a concentration gradient between the interstitial fluid and the descending loop which causes water to diffuse out of the descending loop

14

where is most water absorbed from the collecting duct

cortical region

15

how does urea contribute to concentrating urine

ADH activated urea transporters move urea out of the collecting duct into the interstitium
this can move into the loop of Henle and can recirculate
this helps concentrate urea and forms the hyperosmotic renal medulla
partly due to slow movement in the tubules

16

describe blood flow to the vasa recta

low blood flow so does not remove solutes from the interstitium
help to form the counter current multiplier

17

what receptors stimulate ADH secretion

osmoreceptors

18

what factors increase ADH secretion

increased plasma osmolarity
decreased blood volume/ pressure
nausea
hypoxia
morphine
nicotine

19

what factors decrease ADH secretion

decreased plasma osmolarity
increase blood volume/ pressure

alcohol
clonidine
haloperidol