female reproductive pathology 1 Flashcards Preview

MD3002 post MSA > female reproductive pathology 1 > Flashcards

Flashcards in female reproductive pathology 1 Deck (15):
1

when is proliferative breast disease most common

increases towards menopause and then decreases

2

what are some types of proliferative breast disease

fibrosis
cysts
hyperplasia
adenosis

3

who does gynaecomatstia most commonly affect

adolescent males and elderly males

4

what causes gynaecomastia

estrogen
puberty
endocrine tumours
drugs- spironolactone, alcohol
Kleinfelter's syndrome

5

name some benign breast tumours

fibroadenoma
duct papilloma
adenoma
connective tissue tumour

6

what is a fibroadenoma

mixed tumour
epithelium and stroma well circumscribed
usually young women
may grow during pregnancy

7

describe the epidemiology of breast carcinoma

20% off all cancers in women
1% of tumours are in men
lifetime risk is 1 in 9
commonest cause of death of female 35-55 year olds
commonest cancer in england and wales

8

what is the most common age to be diagnosed with breast cancer

60-64

9

what are the risk factors for breast cancer

alcohol
combined contraceptives
combined HRT
ionising radiation
fatness
smoking

10

what is ductal carcinoma in situ

unilateral tumour confined to ducts

11

what is lobar carcinoma in situ

bilateral tumour confined to lobules

12

what is the most common invasive breast carcinoma

'no special type'

13

what is a less common breast cancer

infiltrating lobular carcinoma, may be multifocal

14

what is paget's disease of the nipple

erosion of the nipple resembling eczema
associated with underlying cancer

15

what type of breast cancer has a better prognosis

estrogen receptor positive