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Neuro Block 2-RG > Encephalitis > Flashcards

Flashcards in Encephalitis Deck (21)
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1

What type of symptoms are associated with encephalitis?

cerebral dysfunction

2

Fever in encephalitis?

yes

3

What is encephalopathy?

altered level of consciousness for 24 hr +

4

What is the most common cause of encephalitis?

idiopathic

5

What is the second most common cause of encephalitis?

herpes viruses

6

Type of WBC found in CSF during encephalitis

lymphocytes

7

MRI abnormality of HSV

temporal > frontal > other

8

Alphaherpesvirus class

class I

9

Most common encephalitis in HIV patients

VZV especially after stem cell transplant

10

Acyclovir is activated by which enzyme?

thymidine kinase (alpha herpesviruses)

11

What lobe of the brain do HSV encephalitis infections mostly affect?

temporal > frontal > other

12

Encephalitis mortality rate

70%

13

What antibody is present in CSF during initial infection?

IgM

14

How is Dx of virus done in CSF?

PCR

15

Microscopic findings of HSV?

-large, multinucleated cells
-Cowdry inclusions

16

Most common viral cause of encephalitis in immunocompromised patients?

VZV (chickenpox or shingles)

17

ADEM

acute disseminated encephalomyelitis

18

ADEM cause

postinfectious

19

SSPE

subacute sclerosising panecephalitis
-6 to 15 yr. post measles
-type of acute disseminated encephalomyelitis

20

Measles virus class

Group V
ssRNA-
enveloped

21

Picorna virus class

Group IV
ssRNA+
nonenveloped