Flashcards in Headaches Deck (19)
What is the pathophysiology of tension headaches?
compression of the greater occipital nerve
Tension headaches: unilateral or bilateral?
What is the treatment for tension headaches?
analgesics and biofeedback
What is the pathophysiology of cluster headaches?
hypothalamic activation of trigeminovascular autonomic system
Describe the pain in a cluster headache
severe unilateral pressure in orbital, supraorbital, or temporal region
What is the treatment for cluster headaches?
supplemental oxygen and sumatriptan
What is the pathophysiology of migraine headaches?
unknown, may be cortical depression
What are the symptoms of a migraine headache?
unilateral throbbing pain that may last hours or days
If someone who has migraines with aura, what do you absolutely not want to give them?
What is the first-line treatment of migraines?
What is the chemical abbreviation for serotonin?
What is serotonin synthesized from?
What enzyme metabolizes serotonin?
monoamine oxygenase (MAO)
Elevated 5-HT levels may preclude what event?
What may cause a migraine headache with relation to serotonin?
Does 5-HT cause vasoconstriction or dilation?
Triptans work how?
agonize 5-HT1B and 5-HT1D receptors causing vasoconstriction and decreasing pro-inflammatory nucleopeptide release
What are the actions of the 5-HT1B and 5-HT1D receptors?
increase K+ permeability and decrease Ca2+ permeability