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Acyclovir

A: antiviral
B: blocks DNA synthesis in virus infected cells
C: HSV-1, HSV-2

1

A: antiviral
B: blocks DNA synthesis in virus infected cells
C: HSV-1, HSV-2

Acyclovir

2

Alendronate

A: bisphosphonate
B:suppress the activity of osteoclast in part via inhibithion of farnesyl pyrophosphate synthesis, inhibit bone resorbtion
C: osteoporosis, bone metastases, hypercalcemia

3

A: bisphosphonate
B:suppress the activity of osteoclast in part via inhibithion of farnesyl pyrophosphate synthesis, inhibit bone resorbtion
C: osteoporosis, bone metastases, hypercalcemia

Alendronate

4

Aminophylline

A: methylxanthine
B: phosphodiesterase inhibition, adenosin receptor antagonist, leads to bronchodialation, cardiac stimulation and increased skeletal muscle strength(diaphragm)
C: asthma, COPD

5

A: methylxanthine
B: phosphodiesterase inhibition, adenosin receptor antagonist, leads to bronchodialation, cardiac stimulation and increased skeletal muscle strength(diaphragm)
C: asthma, COPD

Aminophylline

6

Amitriptyline

A: tricyclic antidepessant (TCA)
B: mixed and variable blockade of NET and SERT
C: major depression not responsive to other drugs

7

A: tricyclic antidepessant (TCA)
B: mixed and variable blockade of NET and SERT
C: major depression not responsive to other drugs

Amitriptyline

8

Amlodipine

A: vasodialator (dihydropyridine)
B: block vascular calcium channels > cardiac calcium channels
C: hypertension, angina

9

A: vasodialator (dihydropyridine)
B: block vascular calcium channels > cardiac calcium channels
C: hypertension, angina

Amlodipine
Nifedipine

10

Nifedipine

A: vasodialator (dihydropyridine)
B: block vascular calcium channels > cardiac calcium channels
C: hypertension, angina

11

Amoxicillin/Clavulanic acid

A: Beta-lactam antibiotics(penicillin) + Beta- lactamase inhibitor
B: synergistic activity against beta-lactamase-producing bacteria
C: gram-positive and gram-negative bacteria

12

A: Beta-lactam antibiotics(penicillin) + Beta- lactamase inhibitor
B: synergistic activity against beta-lactamase-producing bacteria
C: gram-positive and gram-negative bacteria

Amoxicillin/Clavulanic acid

13

Aripiprazole

A: atypical antipsychotic
B: blockade of 5-HT2A receptors > blockade of D2 receptors
C: schizophrenia-improve both posetive and negative symtoms (also in major depression)

14

A: atypical antipsychotic
B: blockade of 5-HT2A receptors > blockade of D2 receptors
C: schizophrenia-improve both posetive and negative symtoms (also in major depression)

Aripiprazole

15

Quetiapine

A: atypical antipsychotic
B: blockade of 5-HT2A receptors > blockade of D2 receptors
C: schizophrenia-improve both posetive and negative symtoms

16

Risperidone

A: atypical antipsychotic
B: blockade of 5-HT2A receptors > blockade of D2 receptors
C: schizophrenia-improve both posetive and negative symtoms (also in bipolar disorder)

17

A: atypical antipsychotic
B: blockade of 5-HT2A receptors > blockade of D2 receptors
C: schizophrenia-improve both posetive and negative symtoms

Aripiprazole
Quetiapine
Risperidone

18

Atorvastatin

A: Statin (HMG-CoA inhibitor)
B: inhibit HMG-CoA reductase, reduces cholesterol synthesis and up-regulate LDL receptors on hepatocytes
C: Atherosclerotic vascular disease, acute coronary syndrome

19

A: Statin (HMG-CoA inhibitor)
B: inhibit HMG-CoA reductase, reduces cholesterol synthesis and up-regulate LDL receptors on hepatocytes
C: Atherosclerotic vascular disease, acute coronary syndrome

Atorvastatin
Rosuvastatin

20

Rosuvastatin

A: Statin (HMG-CoA inhibitor)
B: inhibit HMG-CoA reductase, reduces cholesterol synthesis and up-regulate LDL receptors on hepatocytes
C: Atherosclerotic vascular disease, acute coronary syndrome

21

Atovaquone-proguanil (Malarone)

A: antimalarial drug (quinone-folate antagonist combination)
B: blood schizonticides
C: treatment and chemoprophylaxis of P falciparum infection

22

A: antimalarial drug (quinone-folate antagonist combination)
B: blood schizonticides
C: treatment and chemoprophylaxis of P falciparum infection

Atovaquone-proguanil (Malarone)

23

Atropine

A: anticholinergic drug
B: competative antagonism at all muscarinic receptors
C: in ophthalmology to cause mydriasis and cycloplegia, and as antidote for severe cholinesterase inhibitor poisoning

24

A: anticholinergic drug
B: competative antagonism at all muscarinic receptors
C: in ophthalmology to cause mydriasis and cycloplegia, and as antidote for severe cholinesterase inhibitor poisoning

Atropine
Tropicamide

25

Benzylpenicillin

A: long acting, intramuscular penicillin
B: inhibit transpetidase
C: gram-positive cocci

26

A: long acting, intramuscular penicillin
B: inhibit transpetidase
C: gram-positive cocci

Benzylpenicillin

27

Bevacizumab

A: anticancer drug
B: inhibits VEGF signaling, inhibit tumor vascular permability
C: colerectal cancer

28

A: anticancer drug
B: inhibits VEGF signaling, inhibit tumor vascular permability
C: colerectal cancer

Bevacizumab

29

Bisoprolol

A: antihypertensive drug
B: Beta-1 selective blocker
C: hypertension

30

A: antihypertensive drug
B: Beta-1 selective blocker
C: hypertension

Bisoprolol

31

Bupivacaine

A: local anesthesia
B: blockade of sodium channels
C: spinal anesthetic

32

A: local anesthesia
B: blockade of sodium channels
C: spinal anesthetic

Bupivacaine
Lidocaine

33

Carbamazepine

A: antiseizure drug (tricyclic)
B: blockes high-frequency firing of neuron through action of VG Na+ channels, decreases synaptic relese of glutemate
C: generalized tonic-clonic seizures

34

A: antiseizure drug (tricyclic)
B: blockes high-frequency firing of neuron through action of VG Na+ channels, decreases synaptic relese of glutemate
C: generalized tonic-clonic seizures

Carbamazepine

35

Ceftriaxone

A: third-generation cephalosporin
B: prevent bacterial cell wall synthesis by binding to and inhibiting cell wall transpeptidases
C: many uses including pneumonia, meningitis, pyelonephritis, and gonorrhea

36

A: third-generation cephalosporin
B: prevent bacterial cell wall synthesis by binding to and inhibiting cell wall transpeptidases
C: many uses including pneumonia, meningitis, pyelonephritis, and gonorrhea

Ceftriaxone

37

Cephalexin

A: first-generation cephalosporin
B: prevent bacterial cell wall synthesis by binding to and inhibiting cell wall transpeptidases
C: skin and soft tissue infection and urinary tract infections

38

A: first-generation cephalosporin
B: prevent bacterial cell wall synthesis by binding to and inhibiting cell wall transpeptidases
C: skin and soft tissue infection and urinary tract infections

Cephalexin

39

Ciprofloxacin

A: fluoroquinolone
B: inhibits DNA replication by binding to DNA gyrase and topoisomerase IV
C: urinary tract infections, gastroenteritis, osteomyelitis, antrax

40

A: fluoroquinolone
B: inhibits DNA replication by binding to DNA gyrase and topoisomerase IV
C: urinary tract infections, gastroenteritis, osteomyelitis, antrax

Ciprofloxacin

41

Lidocaine

A: local anesthesia
B: blockade of sodium channels
C: spinal anesthetic

42

Clarithromycin

A: macrolide
B: prevents bacterial protein synthesis by binding to the 50s ribosomal subunit
C: M avium complex

43

A: macrolide
B: prevents bacterial protein synthesis by binding to the 50s ribosomal subunit
C: M avium complex

Clarithromycin

44

Clomiphene

A: ovulation-inducing agent
B: partial agonist at estrogen receptors, causing a surge og gonadotropins which leads to ovulation
C: treatment for women with ovulation disorders who wish to become pregnant

45

A: ovulation-inducing agent
B: partial agonist at estrogen receptors, causing a surge og gonadotropins which leads to ovulation
C: treatment for women with ovulation disorders who wish to become pregnant

Clomiphene

46

Clondine

A: sympathoplegics, centrally acting drug
B: activate Alpha-2 adrenoceptors
C: hypertension

47

A: sympathoplegics, centrally acting drug
B: activate Alpha-2 adrenoceptors
C: hypertension

Clondine

48

Clopidogrel

A: antiplatelet agent
B: irreversible block the ADO receptor on platelets
C: prevents thrombosis after placement of coronary stent

49

A: antiplatelet agent
B: irreversible block the ADO receptor on platelets
C: prevents thrombosis after placement of coronary stent

Clopidogrel

50

Clotrimazole

A: antifungal agent (triazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: topical treatment of Candida

51

A: antifungal agent (imidazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: topical treatment of Candida

Clotrimazole

52

Fluconazole

A: antifungal agent (triazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: excellent CNS penetration, used in fungal meningitis

53

A: antifungal agent (triazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: excellent CNS penetration, used in fungal meningitis

Fluconazole

54

Itraconazole

A: antifungal agent (triazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: broad spectrum: Candida, Cryptococcus, blastomycosis, etc

55

A: antifungal agent (triazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: broad spectrum: Candida, Cryptococcus, blastomycosis, etc

Itraconazole

56

Dabigatran

A: anticoagulant agent
B: oral direct thrombin inhibitor
C: prevention of venous thromboembolism, after hipnreplacement surgery

57

A: anticoagulant agent
B: oral direct thrombin inhibitor
C: prevention of venous thromboembolism, after hipnreplacement surgery

Dabigatran

58

Desmopressin

A: vasopressin receptor agonist
B: relatively selective vasopressin V-2 receptor agonist, decrease the excretion of water in kidney, also acts on extra renal V-2 receptors to increase factor Vlll and von Willebrand factor
C: hemophilia A and von Willebrand factor

59

A: vasopressin receptor agonist
B: relatively selective vasopressin V-2 receptor agonist, decrease the excretion of water in kidney, also acts on extra renal V-2 receptors to increase factor Vlll and von Willebrand factor
C: hemophilia A and von Willebrand factor

Desmopressin

60

Dextromethorphan

A: antitussive
B: strong and partial u-agonist, reduces cough reflex
C: acute debilitating cough

61

A: antitussive
B: strong and partial u-agonist, reduces cough reflex
C: acute debilitating cough

Dextromethorphan

62

Diazepam

A: benzodiazepne
B: Bind to specific GABA(A) receptor subunits at central nervous system (CNS) neuronal synapses facilitating frequency of GABA-mediated chloride ion channel opening- enhance membrane hyperpolarization
C: acute anxiety states

63

A: benzodiazepne
B: Bind to specific GABA(A) receptor subunits at central nervous system (CNS) neuronal synapses facilitating frequency of GABA-mediated chloride ion channel opening- enhance membrane hyperpolarization
C: acute anxiety states

Diazepam
Midazolam

64

Midazolam

A: benzodiazepne
B: Bind to specific GABA(A) receptor subunits at central nervous system (CNS) neuronal synapses facilitating frequency of GABA-mediated chloride ion channel opening- enhance membrane hyperpolarization
C: acute anxiety states

65

Diclofenac

A: NSAID
B: nonselective cox inhibitor
C: prevntion of inflamation

66

A: NSAID
B: nonselective cox inhibitor
C: prevntion of inflamation

Diclofenac

67

Digoxin

A: cardiac glycoside
B: Na+\K+ ATPase inhibition result in reduced Ca2+ expulsion and increased Ca2+ stored in SR, increases contractility, slowes sinus HR, slowed atrioventricular conduction
C:chronic symptomatic heart failure

68

A: cardiac glycoside
B: Na+\K+ ATPase inhibition result in reduced Ca2+ expulsion and increased Ca2+ stored in SR, increases contractility, slowes sinus HR, slowed atrioventricular conduction
C:chronic symptomatic heart failure

Digoxin

69

Diltazem

A: calcium channel blockers
B: nonselective block of L-type calcium channels in vessels and heart, reduces vascular resistance, cardiac rate, and cardiac force result in decreased oxygen demand
C: prophylaxis of angina, hypertension, others

70

A: calcium channel blockers
B: nonselective block of L-type calcium channels in vessels and heart, reduces vascular resistance, cardiac rate, and cardiac force result in decreased oxygen demand
C: prophylaxis of angina, hypertension, others

Diltazem

71

Dinoprostone

A: synthetic PGE2
B: stimulates contraction of the uterus
C: softening of the cervix at term

72

A: synthetic PGE2
B: stimulates contraction of the uterus
C: softening of the cervix at term

Dinoprostone

73

Latanoprost

A: long acting PGF2a derivative
B: acts at FP receptor
C: glaucoma

74

A: long acting PGF2a derivative
B: acts at FP receptor
C: glaucoma

Latanoprost

75

Dobutamine

A: Beta 1 agonist
B: positive inotropic effect
C: cardiogenic shock,macute heart failure

76

A: Beta 1 agonist
B: positive inotropic effect
C: cardiogenic shock,macute heart failure

Dobutamine

77

Doxazosin

A: Alpha-adrenoceptor antagonist
B: blocks Alpha-1, but not Alpha-2, lower BP
C: hypertension, benign prostatic hyperplasia

78

A: Alpha-adrenoceptor antagonist
B: blocks Alpha-1, but not Alpha-2, lower BP
C: hypertension, benign prostatic hyperplasia

Doxazosin

79

Doxorubicin

A: Anthracycline, Cytotoxic antcancer drug
B: Inhibits topoisomerase II, bind DNA, free radical production, bind cellular membranes
C: used as single agent or in combination

80

A: Anthracycline, Cytotoxic antcancer drug
B: Inhibits topoisomerase II, bind DNA, free radical production, bind cellular membranes
C: used as single agent or in combination

Doxorubicin

81

Doxycycline

A: Tetracycline
B: Prevents bacterial protein synthesis by binding to the 30S ribosomal subunit, bacteriostatic activity
C: chlamydia, mycoplasma, spirochetes, etc

82

A: Tetracycline
B: Prevents bacterial protein synthesis by binding to the 30S ribosomal subunit, bacteriostatic activity
C: chlamydia, mycoplasma, spirochetes, etc

Doxycycline

83

Enoxaparine

A: LMW heparin
B: accelerates the action of antithrombin 1000-fold
C: prevention of venous trombosis

84

A: LMW heparin
B: accelerates the action of antithrombin 1000-fold
C: prevention of venous trombosis

Enoxaparine

85

Escitalopram

A: selective serotonin reuptake inhibitor (SSRI)
B: Highly selective blockade of serotonin transporter (SERT), little effect on norepinephrine transporter (NET)
C: major depression

86

A: selective serotonin reuptake inhibitor (SSRI)
B: Highly selective blockade of serotonin transporter (SERT), little effect on norepinephrine transporter (NET)
C: major depression

Escitalopram
Paroxetine

87

Ezetimibe

A: sterol absorption inhibitor
B: blockes sterol transporter NPC1L1 in intestine bruch border, inhibits reabsorption of cholesterol excreted in bile, decreases LDL and phytosterols
C: elevated LDL, phytosterolemia

88

A: sterol absorption inhibitor
B: blockes sterol transporter NPC1L1 in intestine bruch border, inhibits reabsorption of cholesterol excreted in bile, decreases LDL and phytosterols
C: elevated LDL, phytosterolemia

Ezetimibe

89

Finasteride

A: 5a- reductase inhibitor
B: Blocks conversion of dihydrotestosteron
C: benign prostatic hyperplasia

90

A: 5a- reductase inhibitor
B: Blocks conversion of dihydrotestosteron
C: benign prostatic hyperplasia

Finasteride

91

Fluorouracil

A: Fluoropyrimidine
B: Anti-metabolite, interferes with DNA and RNA syntesis
C: Most widely used agent in the treatment of colorectal cancer

92

A: Fluoropyrimidine
B: Anti-metabolite, interferes with DNA and RNA syntesis
C: Most widely used agent in the treatment of colorectal cancer

Fluorouracil

93

Furosemide

A: loop diuretic
B:Inhibition of the Na/K/2Cl in the ascending limb of Henle's loop, marked increase in NaCl excretion
C: pulmonary edema, hypertension, etc

94

A: loop diuretic
B:Inhibition of the Na/K/2Cl in the ascending limb of Henle's loop, marked increase in NaCl excretion
C: pulmonary edema, hypertension, etc

Furosemide
Torasemide

95

Haloperidol

A: typical antipsychotic (butyrophenone)
B: blockade of D2 receptors >> 5-HT2a receptors
C: schizophrenia (positive symptoms)

96

A: typical antipsychotic (butyrophenone)
B: blockade of D2 receptors >> 5-HT2a receptors
C: schizophrenia (positive symptoms)

Haloperidol

97

Hydrochlorothiazide

A: thiazide diuretic
B: Inhibition of the Na/Cl transporter in the distal convoluted tubule, modest increase in NaCl excretion
C: hypertension, mild heart failure

98

A: thiazide diuretic
B: Inhibition of the Na/Cl transporter in the distal convoluted tubule, modest increase in NaCl excretion
C: hypertension, mild heart failure

Hydrochlorothiazide

99

Infliximab

A: Human-mouse chineric IgG1 monoclonial antibody
B:Bind TNF-a, ( a proinflamatory cytokine importent in inflammatory diseases)
C: rheumatoid arthritis

100

A: Human-mouse chineric IgG1 monoclonial antibody
B:Bind TNF-a, ( a proinflamatory cytokine importent in inflammatory diseases)
C: rheumatoid arthritis

Infliximab

101

Insulin lispro

A: rapid-acting insuline
B: activate insulin receptor
C: type 1 and type 2 diabetes

102

A: rapid-acting insuline
B: activate insulin receptor
C: type 1 and type 2 diabetes

Insulin lispro

103

Irbesartan

A: antihypertensive agent (ARB)
B: block AT-1 angiotensin receptors
C: hypertension, heart failure

104

A: antihypertensive agent (ARB)
B: block AT-1 angiotensin receptors
C: hypertension, heart failure

Irbesartan

105

Isoniazid

A: antimycobacterial drug
B: inhibit synthesis of mycolic acid, an essential component of mycobacterial cell walls, bactericidal against susceptible strains of M tuberculosis
C: first-line treatment against tuberculosis

106

A: antimycobacterial drug
B: inhibit synthesis of mycolic acid, an essential component of mycobacterial cell walls, bactericidal against susceptible strains of M tuberculosis
C: first-line treatment against tuberculosis

Isoniazid

107

Rifampin

A: antimycobacterial drug
B: inhibits DNA- dependent RNA polymerase, thereby blocking production of RNA
C: tuberculosis, atypical mycobacterial infections

108

A: antimycobacterial drug
B: inhibits DNA- dependent RNA polymerase, thereby blocking production of RNA
C: tuberculosis, atypical mycobacterial infections

Rifampin

109

Isotretinoin

A: synthetic retinoid
B: inhibit sebaceous gland size and function
C: severe cystic acne

110

A: synthetic retinoid
B: inhibit sebaceous gland size and function
C: severe cystic acne

Isotretinoin

111

Isosorbide mononitrate

A: nitrate
B: Releases nitric oxide in smooth muscle, whitch activates guanylyl cyclase and increases cGMP, leads to smooth muscle relaxation especially in vessels
C: angina, acute coronary syndrome

112

A: nitrate
B: Releases nitric oxide in smooth muscle, whitch activates guanylyl cyclase and increases cGMP, leads to smooth muscle relaxation especially in vessels
C: angina, acute coronary syndrome

Isosorbide mononitrate

113

Levodopa/benserazide

A: antiparkinsom drug
B: transported into CNS and coverted to dopamine, ameliorates all symptoms of parkinson's disease
C: parkingsons disease

114

A: antiparkinsom drug
B: transported into CNS and coverted to dopamine, ameliorates all symptoms of parkinson's disease
C: parkingsons disease

Levodopa/benserazide

115

Levonorgestrel

A:

116

Mebendazole

A: antihelminthic drug
B: inhibiting microtubule synthesis
C: ascariasis, trichuriasis, hookworm and pinworm infection

117

A: antihelminthic drug
B: inhibiting microtubule synthesis
C: ascariasis, trichuriasis, hookworm and pinworm infection

Mebendazole

118

Memantine

A: cognetive enhancer
B: NMDA receptor channel blocker
C: alzheimer's disease

119

A: cognetive enhancer
B: NMDA receptor channel blocker
C: alzheimer's disease

Memantine

120

Metformin

A: biguanides
B: reduced hepatic and renal gluconeogenesis, decreases endogenous glucose production
C: type 2 diabetes

121

A: biguanides
B: reduced hepatic and renal gluconeogenesis, decreases endogenous glucose production
C: type 2 diabetes

Metformin

122

Methotrexate

A: Disease-modifying antirheumatic drug
B: synthetic antimetabolite, acumulates intracellularly, inhibits AMP deaminase, acumulates AMP, leads to less inflamaton
C: rheumatoid arthritis

123

A: Disease-modifying antirheumatic drug
B: synthetic antimetabolite, acumulates intracellularly, inhibits AMP deaminase, acumulates AMP, leads to less inflamaton
C: rheumatoid arthritis

Methotrexate

124

Metronidazole

A: miscellaneous antimicrobial
B: disruption of electron transport chain, bactericidal against anaerobic bacteria and protozoa
C: C difficile colitis

125

A: miscellaneous antimicrobial
B: disruption of electron transport chain, bactericidal against anaerobic bacteria and protozoa
C: C difficile colitis

Metronidazole

126

Metoprolol

A: sympathetic antagonist
B: block Beta1 > Beta2, lower HR and BP
C: hypertension

127

A: sympathetic antagonist
B: block Beta1 > Beta2, lower HR and BP
C: hypertension

Metoprolol
Nebivolol

128

Montelukast

A: Leukotriene antagonist
B: blocks leukotriene D4 receptor, block airway responce to exercise and antigen challenge
C: prophylaxis of asthma

129

A: Leukotriene antagonist
B: blocks leukotriene D4 receptor, block airway responce to exercise and antigen challenge
C: prophylaxis of asthma

Montelukast

130

Methylprednisolone

A: corticosteroid, systemic
B: alters gene expression, reduces mediators of inflammation
C: asthma

131

A: corticosteroid, systemic
B: alters gene expression, reduces mediators of inflammation
C: asthma

Methylprednisolone

132

Morphine

A: strong opioid agonist
B: strong u-receptor agonist, analgesia, relif of anxiety, sedation, slowes gastrointestinal transit
C: severe pain, adjunct in anesthesia, pulmonary edema

133

A: strong opioid agonist
B: strong u-receptor agonist, analgesia, relif of anxiety, sedation, slowes gastrointestinal transit
C: severe pain, adjunct in anesthesia, pulmonary edema

Morphine

134

Nebivolol

A: sympathetic antagonist
B: block Beta1 > Beta2, lower HR and BP
C: hypertension

135

Omeprazole

A: proton pump inhibitor
B: Irreversible blockade of H+/K+ATPase pump in active parietal cells of stomach, long-lasting reduction of stimulated and nocturnal acid secration
C: peptic ulcer disease

136

A: proton pump inhibitor
B: Irreversible blockade of H+/K+ATPase pump in active parietal cells of stomach, long-lasting reduction of stimulated and nocturnal acid secration
C: peptic ulcer disease

Omeprazole

137

Ondansetron

A: antiemetic drug
B: 5-HT3 blockade in gut and CNS, Extremely effective in preventing chemotheraphy induced and postoperative nausea and vomiting
C: postoperative emesis

138

A: antiemetic drug
B: 5-HT3 blockade in gut and CNS, Extremely effective in preventing chemotheraphy induced and postoperative nausea and vomiting
C: postoperative emesis

Ondansetron

139

Oseltamivir

A: antiviral agent
B: neuramidase inhibitor, interfere with the release of progeny influenca virus from infected host cell, halting spread of infection
C: influenza

140

A: antiviral agent
B: neuramidase inhibitor, interfere with the release of progeny influenca virus from infected host cell, halting spread of infection
C: influenza

Oseltamivir

141

Oxytocin

A: pituitary hormone
B: activates oxytocin receptor, increases uterine contractions
C: induction of labor

142

A: pituitary hormone
B: activates oxytocin receptor, increases uterine contractions
C: induction of labor

Oxytocin

143

Pancreatin

A: pancreatic supplement
B: replaces enzymes from animal extracts, improves digestion of diatary fat, protein, and carbohydrates
C: pancreatetomy

144

A: pancreatic supplement
B: replaces enzymes from animal extracts, improves digestion of diatary fat, protein, and carbohydrates
C: pancreatetomy

Pancreatin

145

Paroxetine

A: selective serotonin reuptake inhibitor (SSRI)
B: Highly selective blockade of serotonin transporter (SERT), little effect on norepinephrine transporter (NET)
C: major depression

146

Perindopril

A: angiotensin-coverting enzyme inhibitor
B: inhibit angiotensin converting enzyme, reduces vasoconstriction and aldosteron secretion
C: heart failure

147

A: angiotensin-coverting enzyme inhibitor
B: inhibit angiotensin converting enzyme, reduces vasoconstriction and aldosteron secretion
C: heart failure

Perindopril

148

Permethrin

A: dermatologic application
B: ectoparasiticide
C: scabis

149

A: dermatologic application
B: ectoparasiticide
C: scabis

Permethrin

150

Povidone iodine

A: halogen
B: kill bacteria, fungi and lipid viruses
C: antiseptic

151

A: halogen
B: kill bacteria, fungi and lipid viruses
C: antiseptic

Povidone iodine

152

Procainamide

A: class 1A antiarrhythmic
B: slowes conduction velocity and pacemaker rate
C: atrial arrhytmias

153

A: class 1A antiarrhythmic
B: slowes conduction velocity and pacemaker rate
C: atrial arrhytmias

Procainamide

154

Propranolol

A: class 2 antiarrhythmic
B: Beta-adrenoceptor blockade slows AV node automatisity and AV nodal conduction velocity
C: prevention of sudden death

155

A: class 2 antiarrhythmic
B: Beta-adrenoceptor blockade slows AV node automatisity and AV nodal conduction velocity
C: prevention of sudden death

Propranolol

156

Ranitidine

A: H2 blocker
B: blocks H2, reduces nocturnal acid secration
C: acid reflux

157

A: H2 blocker
B: blocks H2, reduces nocturnal acid secration
C: acid reflux

Ranitidine

158

Rivaroxaban

A: anticoagulant
B: direct factor Xa inhibitor
C:prevebtion of venous thrombolism

159

A: anticoagulant
B: direct factor Xa inhibitor
C:prevebtion of venous thrombolism

Rivaroxaban

160

Sildenafil

A: phosphodiesterase inhibitor
B: incrases cGMP, leads to relaxation of smooth muscles
C: erectile dysfunction

161

A: phosphodiesterase inhibitor
B: incrases cGMP, leads to relaxation of smooth muscles
C: erectile dysfunction

Sildenafil

162

Spironolactone

A: potassium-sparing diuretic
B: Pharmacologic antagonist of aldosteron in collecting tubules, Weak antagonism of androgen receptor, reduces Na retension
C: postmyocardial infection

163

A: potassium-sparing diuretic
B: Pharmacologic antagonist of aldosteron in collecting tubules, Weak antagonism of androgen receptor, reduces Na retension
C: postmyocardial infection

Spironolactone

164

Tamsulosin

A: sympathetic antagonists
B: slightly selective for Alpha-1A, blockade of prostaic smooth muscle more the vascular smooth muscle
C: benign prostatic hyperplasia

165

A: sympathetic antagonists
B: slightly selective for Alpha-1A, blockade of prostaic smooth muscle more the vascular smooth muscle
C: benign prostatic hyperplasia

Tamsulosin

166

Terbinafine

A: antifungal
B: inhibits epoxidation of squalene in fungi, increased levels are toxic to them, reduces ergosterol
C: mucocutaneoys fungsl infection

167

A: antifungal
B: inhibits epoxidation of squalene in fungi, increased levels are toxic to them, reduces ergosterol
C: mucocutaneoys fungsl infection

Terbinafine

168

Tolterodine

A: antimuscarinic agent
B: M-3 selective block
C: urinary incontinence

169

A: antimuscarinic agent
B: M-3 selective block
C: urinary incontinence

Tolterodine

170

Torasemide

A: loop diuretic
B:Inhibition of the Na/K/2Cl in the ascending limb of Henle's loop, marked increase in NaCl excretion
C: pulmonary edema, hypertension, etc

171

Trihexyphenidyl

A: antimuscarinic agent
B: antagonist at M receptors in basal ganglia, reduces tremor and rgidity
C: parkingson's disease

172

A: antimuscarinic agent
B: antagonist at M receptors in basal ganglia, reduces tremor and rgidity
C: parkingson's disease

Trihexyphenidyl

173

Tropicamide

A: anticholinergic drug
B: competative antagonism at all muscarinic receptors
C: in ophthalmology to cause mydriasis and cycloplegia, and as antidote for severe cholinesterase inhibitor poisoning

174

Valproate acid

A: antiseizure drug
B: blocks high-frequency firing of neuron, modifies amino acid metabolism
C: myoclonic seizures

175

A: antiseizure drug
B: blocks high-frequency firing of neuron, modifies amino acid metabolism
C: myoclonic seizures

Valproate acid

176

Warfarin

A: anticoagulant
B: cause blockad of y-carboxylation of several endogenous produced coagulation factors, making the biological inactive
C: DVT profylaxis

177

A: anticoagulant
B: cause blockad of y-carboxylation of several endogenous produced coagulation factors, making the biological inactive
C: DVT profylaxis

Warfarin

178

Zolmitriptan

A: anti migrane drug (triptan)
B: 5-HT(1D/1B) agonist
C: migrane

179

A: anti migrane drug (triptan)
B: 5-HT(1D/1B) agonist
C: migrane

Zolmitriptan

180

Zolpidem

A: newer hypnotic
B: bind selectivly to a subunit og GABA(A) acting like benzodiasapines, rapid onset of hypnosis
C: sleep disorders

181

A: newer hypnotic
B: bind selectivly to a subunit og GABA(A) acting like benzodiasapines, rapid onset of hypnosis
C: sleep disorders

Zolpidem

182

Salbutamol

A: selective Beta2 agonist
B: prompt, efficacious broncodialation
C: acute asthmatic broncospasm

183

A: selective Beta2 agonist
B: prompt, efficacious broncodialation
C: acute asthmatic broncospasm

Salbutamol

184

Physostigmine

A: intermediate-acting cholinesterase inhibitor
B: blocks AChE
C: myastavia gravis

185

A: intermediate-acting cholinesterase inhibitor
B: blocks AChE
C: myastavia gravis

Physostigmine

186

Ursodeoxycholic acid

A: bile acid theraphy drug
B: reduces cholesterol secration into bile, dissolve gallstones,
C: gallstone

187

A: bile acid theraphy drug
B: reduces cholesterol secration into bile, dissolve gallstones,
C: gallstone

Ursodeoxycholic acid

188

Loratadine

A: second-generation H1 blocker
B: blocks H1 receptors, prevents releace of histamine
C: hey fever

189

A: second-generation H1 blocker
B: blocks H1 receptors, prevents releace of histamine
C: hey fever

Loratadine

190

Etoricoxib

A: NSAID
B: cox-2 selective inhibitor
C: block peripheral inflamation

191

A: NSAID
B: cox-2 selective inhibitor
C: block peripheral inflamation

Etoricoxib

192

Ephedrine

A: agonist of alpha and beta
B: same as A
C: not used

193

A: agonist of alpha and beta
B: same as A
C: not used

Ephedrine

194

Levonorgestrel

A: synthetic progrestin
B: inhibit ovulation
C: morning after pil

195

A: synthetic progrestin
B: inhibit ovulation
C: morning after pil

Levonorgestrel

196

Mesalazine

A: antiinflamatory
B: inhibit eicosanoid inflamatory mediators
C: inflamatory bowel disease

197

A: antiinflamatory
B: inhibit eicosanoid inflamatory mediators
C: inflamatory bowel disease

Mesalazine

198

Piracetam

A: nootropic
B: increases cognitive function
C: dementia

199

A: nootropic
B: increases cognitive function
C: dementia

Piracetam

200

Adrenalin

A: catochlomamine
B: adrengenic agonist
C: hypotension

201

A: catochlomamine
B: adrengenic agonist
C: hypotension

Adrenalin

202

Acetylsalcylic acid

A: NSAID
B: cox inhibition
C: prevention of heart attack

203

A: NSAID
B: cox inhibition
C: prevention of heart attack

Acetylsalcylic acid

204

Amiodarone

A: class 3 antiarrhytmic
B: bloks I(kr), I(Na), I(Ca-L), prolongs action potential an QT interval
C: serious ventricular arrhytmias

205

A: class 3 antiarrhytmic
B: bloks I(kr), I(Na), I(Ca-L), prolongs action potential an QT interval
C: serious ventricular arrhytmias

Amiodarone

206

Co-triamaxazole

A: folate antagonist
B: Synergistic combination of folate antagonists blocks purine production and nucleic acid synthesis, bactericidal activity against susceptible bacteria
C: UTI

207

A: folate antagonist
B: Synergistic combination of folate antagonists blocks purine production and nucleic acid synthesis, bactericidal activity against susceptible bacteria
C: UTI

Co-triamaxazole