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Flashcards in Drugs Used In Diabetes Deck (77)
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Insulins

Rapid-acting: Lispro, aspart, glulisine
Short-acting: Regular
Intermediate-acting: NPH
Long-acting: Detemir, glargine

1

Lispro

Rapid-acting:Insulin

2

aspart

Rapid-acting:Insulin

3

glulisine

Rapid-acting:Insulin

4

Regular

Short-acting:Insulin

5

NPH

Intermediate-acting: Insulin

6

Detemir

Long-acting: Insulin

7

glargine

Long-acting: Insulin

8

Rapid-acting:insulin

Lispro
aspart
glulisine

9

Short-acting:Insulin

Regular

10

Intermediate-acting: Insulin

NPH

14

Long-acting: Insulin

Detemir
Glargine

15

Insulins
Mechanism of action

Activate insulin receptor

16

Activate insulin receptor

Insulins
Mechanism of action

17

Insulins
Effects

Reduce circulating glucose
Promote glucose transport and oxidation;glycogen, lipid, protein synthese; and regulation of gene expression

18

Reduce circulating glucose
Promote glucose transport and oxidation;glycogen, lipid, protein synthese; and regulation of gene expression

Insulins
Effects

19

Insulins
Clinical applications

Type 1 and type 2 diabetes

20

Type 1 and type 2 diabetes

Insulins
Clinical applications

21

Insulins
Toxicity

Hypoglycemia
Weight gain
Lipodystrophy (rare)

22

Hypoglycemia
Weight gain
Lipodystrophy (rare)

Insulins
Toxicity

23

Sulfonylureas

Glipizide
Glyburide
Glimepiride

24

Glipizide

Sulfonylurea

25

Glyburide

Sulfonylurea

26

Glimepiride

Sulfonylurea

27

Sulfonylurea
Mechanism of action

Insulin secretagogues: close K+ Channels in beta cells
Increase insulin release

28

Insulin secretagogues: close K+ Channels in beta cells
Increase insulin release

Sulfonylurea
Mechanism of action

29

Sulfonylurea
Effects

In patients with functioning beta cells, reduce circulating glucose
Increase glycogen, fat, and protein formation
Gene regulation

30

In patients with functioning beta cells, reduce circulating glucose
Increase glycogen, fat, and protein formation
Gene regulation

Sulfonylurea
Effects

31

Sulfonylurea
Clinical applications

Type 2 diabetes

32

Sulfonylurea
Clinical applications

Type 2 diabetes