Flashcards in Diuretics Deck (64)
Loading flashcards...
0
Carbonic anhydrase inhibitors
Acetazolamide
Brinzolamide
Dorszolamide
1
Acetazolamide
Carbonic anhydrase inhibitor
2
Brinzolamide
Carbonic anhydrase inhibitor
(Topical for glaucoma)
3
Dorszolamide
Carbonic anhydrase inhibitor
(Topical for glaucoma)
4
Carbonic anhydrase inhibitor
Mechanism of action
Inhibition of the enzyme prevents dehydration of H2CO3 and hydration of CO2 in the proximal convoluted tubule
5
Inhibition of the enzyme prevents dehydration of H2CO3 and hydration of CO2 in the proximal convoluted tubule
Carbonic anhydrase inhibitor
Mechanism of action
6
Acetazolamide
Mechanism of action
Inhibition of the enzyme prevents dehydration of H2CO3 and hydration of CO2 in the proximal convoluted tubule
7
Carbonic anhydrase inhibitor
Effects
-Reduces reabsorbtion of HCO3- , causing self-limited diuresis
-hyperchloremic metabolic acidosis reduces body ph, reduces intraocular pressure
8
Carbonic anhydrase inhibitor
Clinical applications
Glaucoma, moutain sickness, edema with alkalosis
9
Glaucoma, moutain sickness, edema with alkalosis
Carbonic anhydrase inhibitor
Clinical applications
10
Loop diuretics
Furosemide
Bumetanide
Torsemide
Ethacrynic acid
11
Furosemide
Loop diuretic (sulfonamide)
12
Bumetanide
Loop diuretic (sulfonamide)
13
Torsemide
Loop diuretic (sulfonamide)
14
Ethacrynic acid
Loop diuretic (not sulfonamide)
15
Furosemide
Mechanism of action
Inhibition of the Na/K/2Cl in the ascending limb of Henle's loop
16
Inhibition of the Na/K/2Cl in the ascending limb of Henle's loop
Furosemide
Mechanism of action
17
Loop diuretics
Mechanism of action
Inhibition of the Na/K/2Cl in the ascending limb of Henle's loop
18
Loop diuretics
Effects
-Marked increase in NaCl excretion
-Some K wasting
-Hypokalemic metabolic alkalosis
-Increased urine Ca and Mg
19
-Marked increase in NaCl excretion
-Some K wasting
-Hypokalemic metabolic alkalosis
-Increased urine Ca and Mg
Loop diuretics
Effects
20
Loop diuretics
Clinical applications
-Pulmonary edema.
-Peripheral edema.
-Hypertension.
-Acute hypercalcemia.
-Acute hyperkalemia.
-Renal failure anion overdose (bromide, fluoride,
and iodide.
21
-Pulmonary edema.
-Peripheral edema.
-Hypertension.
-Acute hypercalcemia.
-Acute hyperkalemia.
-Renal failure anion overdose (bromide, fluoride,
and iodide.
Loop diuretics
Clinical applications
22
Loop diuretics
Toxicity
Ototoxicity
Hypovolemia
K wasting
Hyperuricemia
Hypomagnesemia
23
Thiazide diuretics
Hydrochlorothiazide
Chlorothiazide
Bendroflumethiazide
Hydroflumethazide
Methyclothiazide
Indapamide
24
Hydrochlorothiazide
Thiazide diuretic
25
Chlorothiazide
Thiazide diuretic
26
Hydroflumethazide
Thiazide diuretic
27
Methyclothiazide
Thiazide diuretic
28
Indapamide
Thiazide diuretic
29
