Flashcards in Random Urinary Drug Deck (40):
0
Alpha-adrenoceptor antagonist
Tamsulosin
1
Tamsulosin
Alpha-adrenoceptor antagonist
2
Tamsulosin
Mechanism of action
Tamosulosin is slightly selective for Alpha-1A
3
Slightly selective for Alpha-1A
Tamsulosin
Mechanism of action
4
Tamsulosin
Effects
Alpha-1A blockade may relax prostatic smooth muscles more than vascular smooth muscle
5
Alpha-1A blockade may relax prostatic smooth muscles more than vascular smooth muscle
Tamsulosin
Effects
6
Tamsulosin
Clinical applications
Benign prostatic hyperplasia
7
Benign prostatic hyperplasia
Tamsulosin
Clinical applications
8
Tamsulosin
Toxicity
Orthostatic hypotension may be less common with this subtype
9
Orthostatic hypotension may be less common with this subtype
Tamsulosin
Toxicity
10
5a- reductase inhibitors
Finasteride
Dustasteride
11
Finasteride
5a- reductase inhibitor
12
Dustasteride
5a- reductase inhibitor
13
Finasteride
Mechanism of action
Blocks conversion of dihydrotestosteron
14
Blocks conversion of dihydrotestosteron
Finasteride
Mechanism of action
15
Finasteride
Clinical application
Benign prostatic hyperplasia
16
Allopurinol
Xanthine oxidase inhibitor
17
Xanthine oxidase inhibitor
Allopurinol
18
Allopurinol
Indications
First-line agent for the treatment of chronic gout
19
First-line agent for the treatment of chronic gout
Allopurinol
20
Desmopressin
Long-acting synthetic analog of vasopressin with minimal pressor activity and an antidiuretic-to-pressor ratio 4000 times that of vasopressin
21
Long-acting synthetic analog of vasopressin with minimal pressor activity and an antidiuretic-to-pressor ratio 4000 times that of vasopressin
Desmopressin
22
Desmopressin
Clinical applications
Pituitary diabetes insipidus
Pediatric primary nocturnal enuresis
Hemophilia A and von Willebrand disease
23
Pituitary diabetes insipidus
Pediatric primary nocturnal enuresis
Hemophilia A and von Willebrand disease
Desmopressin
Clinical applications
24
Desmopressin
Vasopressin
Vasopressin receptor agonists
25
Vasopressin receptor agonists
Desmopressin
Vasopressin
26
Desmopressin
Vasopressin receptor agonist
27
Desmopressin
Mechanism of action
Relatively selective vasopressin V2 receptor agonist
28
Relatively selective vasopressin V2 receptor agonist
Desmopressin
Mechanism of action
29
Desmopressin
Effects
Acts in the kidney colecting duct cells to decrease the excretion of water
Acts on extra renal V2 receptors to increase factor ( V||| ) and von Willbrand factor
30
Acts in the kidney colecting duct cells to decrease the excretion of water
Acts on extra renal V2 receptors to increase factor ( V||| ) and von Willbrand factor
Desmopressin
Effects
31
Desmopressin
Toxicity
Gastrointestinal disturbances
Headache
Hyponatremia
Allergic reactions
32
Phosphodiesterase isoform 5 (PDE-5) inhibitors
Sildenafil (Viagra)
Tadalafil
Vardenafil
33
Sildenafil (Viagra)
Phosphodiesterase isoform 5 (PDE-5) inhibitor
34
Tadalafil
Phosphodiesterase isoform 5 (PDE-5) inhibitor
35
Vardenafil
Phosphodiesterase isoform 5 (PDE-5) inhibitor
36
Phosphodiesterase isoform 5 (PDE-5) inhibitor
Clinical applications
Erectile dysfunction
Possible use: pulmonary arterial hypertension
( cystic fibrosis )
( BPH )
37
Alprostadil
PGE1 anolog
38
PGE1 anolog
Alprostadil
39