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Flashcards in Random Urinary Drug Deck (40):
0

Alpha-adrenoceptor antagonist

Tamsulosin

1

Tamsulosin

Alpha-adrenoceptor antagonist

2

Tamsulosin
Mechanism of action

Tamosulosin is slightly selective for Alpha-1A

3

Slightly selective for Alpha-1A

Tamsulosin
Mechanism of action

4

Tamsulosin
Effects

Alpha-1A blockade may relax prostatic smooth muscles more than vascular smooth muscle

5

Alpha-1A blockade may relax prostatic smooth muscles more than vascular smooth muscle

Tamsulosin
Effects

6

Tamsulosin
Clinical applications

Benign prostatic hyperplasia

7

Benign prostatic hyperplasia

Tamsulosin
Clinical applications

8

Tamsulosin
Toxicity

Orthostatic hypotension may be less common with this subtype

9

Orthostatic hypotension may be less common with this subtype

Tamsulosin
Toxicity

10

5a- reductase inhibitors

Finasteride
Dustasteride

11

Finasteride

5a- reductase inhibitor

12

Dustasteride

5a- reductase inhibitor

13

Finasteride
Mechanism of action

Blocks conversion of dihydrotestosteron

14

Blocks conversion of dihydrotestosteron

Finasteride
Mechanism of action

15

Finasteride
Clinical application

Benign prostatic hyperplasia

16

Allopurinol

Xanthine oxidase inhibitor

17

Xanthine oxidase inhibitor

Allopurinol

18

Allopurinol
Indications

First-line agent for the treatment of chronic gout

19

First-line agent for the treatment of chronic gout

Allopurinol

20

Desmopressin

Long-acting synthetic analog of vasopressin with minimal pressor activity and an antidiuretic-to-pressor ratio 4000 times that of vasopressin

21

Long-acting synthetic analog of vasopressin with minimal pressor activity and an antidiuretic-to-pressor ratio 4000 times that of vasopressin

Desmopressin

22

Desmopressin
Clinical applications

Pituitary diabetes insipidus
Pediatric primary nocturnal enuresis
Hemophilia A and von Willebrand disease

23

Pituitary diabetes insipidus
Pediatric primary nocturnal enuresis
Hemophilia A and von Willebrand disease

Desmopressin
Clinical applications

24

Desmopressin
Vasopressin

Vasopressin receptor agonists

25

Vasopressin receptor agonists

Desmopressin
Vasopressin

26

Desmopressin

Vasopressin receptor agonist

27

Desmopressin
Mechanism of action

Relatively selective vasopressin V2 receptor agonist

28

Relatively selective vasopressin V2 receptor agonist

Desmopressin
Mechanism of action

29

Desmopressin
Effects

Acts in the kidney colecting duct cells to decrease the excretion of water

Acts on extra renal V2 receptors to increase factor ( V||| ) and von Willbrand factor

30

Acts in the kidney colecting duct cells to decrease the excretion of water

Acts on extra renal V2 receptors to increase factor ( V||| ) and von Willbrand factor

Desmopressin
Effects

31

Desmopressin
Toxicity

Gastrointestinal disturbances
Headache
Hyponatremia
Allergic reactions

32

Phosphodiesterase isoform 5 (PDE-5) inhibitors

Sildenafil (Viagra)
Tadalafil
Vardenafil

33

Sildenafil (Viagra)

Phosphodiesterase isoform 5 (PDE-5) inhibitor

34

Tadalafil

Phosphodiesterase isoform 5 (PDE-5) inhibitor

35

Vardenafil

Phosphodiesterase isoform 5 (PDE-5) inhibitor

36

Phosphodiesterase isoform 5 (PDE-5) inhibitor
Clinical applications

Erectile dysfunction

Possible use: pulmonary arterial hypertension
( cystic fibrosis )
( BPH )

37

Alprostadil

PGE1 anolog

38

PGE1 anolog

Alprostadil

39

Alprostadil
Clinical application

Erectile dysfunction