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Flashcards in Drugs Used In Asthma Deck (90):
0

Beta agonists

Albuterol
Salmeterol
Metaproterenol
Terbutaline
Formoterol
Epinephrine
Isoproterenol

1

Albuterol

Selective Beta2 agonist

2

Salmeterol

Selective Beta2 agonist

3

Metaproterenol

Selective Beta2 agonist

4

Terbutaline

Selective Beta2 agonist

5

Formoterol

Selective Beta2 agonist

6

Albuterol
Mechanism of action

Selective Beta2 agonist

7

Salmeterol
Mechanism of action

Selective Beta2 agonist

8

Albuterol
Effect

Prompt, efficacious bronchodilation

9

Prompt, efficacious bronchodilation

Albuterol
Effect

10

Salmeterol
Effects

Slow onset, primarily preventive action; potentiates corticosteroid effects

11

Slow onset, primarily preventive action; potentiates corticosteroid effects

Salmeterol
Effects

12

Albuterol
Clinical applications

Asthma
Chronic obstructive pulmonary disease (COPD)
Drug of choice in acute asthmatic bronchospasm

13

Asthma
Chronic obstructive pulmonary disease (COPD)
Drug of choice in acute asthmatic bronchospasm

Albuterol
Clinical applications

14

Salmeterol
Clinical applications

Asthma prophylaxis

15

Asthma prophylaxis

Salmeterol
Clinical applications

16

Albuterol
Toxicity

Tremor
Tachycardia
Overdose: arrhythmias

17

Tremor
Tachycardia
Overdose: arrhythmias

Albuterol
Salmeterol

Toxicity

18

Salmeterol
Toxicity

Tremor
Tachycardia
Overdose: arrhythmias

19

Epinephrine

Nonselective Alpha and Beta agonist

20

Nonselective Alpha and Beta agonist

Epinephrine

21

Epinephrine
Mechanism of action

Nonselective Alpha and Beta agonist

22

Epinephrine
Effects

Bronchodilation plus all other sympathomimetic effects on cardiovascular and other organ systems

23

Bronchodilation plus all other sympathomimetic effects on cardiovascular and other organ systems

Epinephrine
Effects

24

Epinephrine
Clinical applications

Anaphylaxis
Asthma
(Others)
Rarely used for asthma (Beta2-selective agents preferred)

25

Anaphylaxis
Asthma
(Others)
Rarely used for asthma (Beta2-selective agents preferred)

Epinephrine
Clinical applications

26

Isoproterenol

Beta1 and Beta2 agonist

27

Beta1 and Beta2 agonist

Isoproterenol

28

Isoproterenol
Mechanism of action

Beta1 and Beta2 agonist

29

Isoproterenol
Effects

Bronchodilation plus powerful cardiovascular effects

30

Bronchodilation plus powerful cardiovascular effects

Isoproterenol
Effects

31

Isoproterenol
Clinical applications

Asthma (but Beta2-selective agents preferred)

32

Asthma (but Beta2-selective agents preferred)

Isoproterenol
Clinical applications

33

Corticosteroids, inhaled

Fluticasone
Beclomethasone
Budesonide
Flunisolide

34

Fluticasone

Corticosteroid, inhaled

35

Beclomethasone

Corticosteroid, inhaled

36

Budesonide

Corticosteroid, inhaled

37

Flunisolide

Corticosteroid, inhaled

38

Corticosteroids, inhaled
Mechanism of action

Alters gene expression

39

Corticosteroids, inhaled
Mechanism of action

Alters gene expression

40

Alters gene expression

Corticosteroids, inhaled
Corticosteriods, systemic

Mechanism of action

41

Corticosteroids, systemic
Mechanism of action

Alters gene expression

42

Fluticasone
Mechanism of action

Alters gene expression

43

Budesonide
Mechanism of action

Alters gene expression

44

Beclomethasone
Mechanism of action

Alters gene expression

45

Corticosteriods, inhaled
Effects

Reduces mediators of inflammation
Powerful prophylaxis of exacerbations

46

Reduces mediators of inflammation
Powerful prophylaxis of exacerbations

Corticosteriods, systemic


Effects

47

Corticosteriods, systemic
Effects

Reduces mediators of inflammation
Powerful prophylaxis of exacerbations

48

Prednisone
Effects

Reduces mediators of inflammation
Powerful prophylaxis of exacerbations

49

Methylprednisolone
Effects

Reduces mediators of inflammation
Powerful prophylaxis of exacerbations

50

Betclomethasone
Effects

Reduces mediators of inflammation
Powerful prophylaxis of exacerbations

51

Budesonide
Effects

Reduces mediators of inflammation
Powerful prophylaxis of exacerbations

52

Corticosteroids, inhaled
Clinical applications

Asthma
Adjunct in COPD
Hay fever (nasal)

53

Asthma
Adjunct in COPD
Hay fever (nasal)

Corticosteroids, inhaled
Clinical applications

54

Corticosteroids, systemic
Clinical applications

Asthma
Adjunct in COPD

55

Asthma
Adjunct in COPD

Corticosteroids, systemic
Clinical applications

56

Corticosteroids

Fluticasone
Beclomethasone
Budesonide
Flunisolide
Prednisone
Methylprednisolone

57

Fluticasone
Beclomethasone
Budesonide
Flunisolide
Prednisone
Methylprednisolone

Corticosteroids

58

Stabilizers of mast and other cells

Cromolyn
Nedocromil

59

Cromolyn

Stabilizers of mast and other cells

60

Nedocromil

Stabilizers of mast and other cells

61

Nedocromil
Cromolyn

Mechanism of action

Alter function of delayed chloride channels
Inhibits inflammatory cell activation

62

Alter function of delayed chloride channels
Inhibits inflammatory cell activation

Nedocromil
Cromolyn

Mechanism of action

63

Nedocromil
Cromolyn

Effects

Prevents acute bronchospasm

64

Prevents acute bronchospasm

Nedocromil
Cromolyn

Effects

65

Nedocromil
Cromolyn

Clinical applications

Asthma
(other routes used for ocular, nasal ang GI allergy)

66

Asthma
(other routes used for ocular, nasal ang GI allergy)

Nedocromil
Cromolyn

Clinical applications

67

Methylxanthine

Theophylline

68

Theophylline

Methylxanthine

69

Theophylline
Mechanism of action

Uncertain
Phosphodiesterase inhibition
Adenosine receptor antagonist

70

Uncertain
Phosphodiesterase inhibition
Adenosine receptor antagonist

Theophylline
Mechanism of action

71

Theophylline
Effects

Bronchodilation
Cardiac stimulation
Increased skeletal muscle strength (diaphragm)

72

Bronchodilation
Cardiac stimulation
Increased skeletal muscle strength (diaphragm)

Theophylline
Effects

73

Theophylline
Clinical applications

Asthma
COPD

74

Asthma
COPD

Theophylline
Clinical applications

75

Leukotriene antagonists

Montelukast
Zafirlukast

76

Montelukast

Leukotriene antagonist

77

Zafirlukast

Leukotriene antagonist

78

Montelukast
Mechanism of action

Block leukotriene D4 receptors

79

Block leukotriene D4 receptors

Montelukast
Zafirlukast

Mechanism of action

80

Montelukast
Effects

Block airway response to exercise and antigen challange

81

Block airway response to exercise and antigen challange

Montelukast
Zafirlukast

Effects

82

Montelukast
Clinical applications

Prophylaxis of asthma especially in children and in aspirine-induced asthma

83

Prophylaxis of asthma especially in children and in aspirine-induced asthma

Montelukast
Zafirlukast

Clinical applications

84

IgE antibody

Omalizumab

85

Omalizumab

IgE antibody

86

Omalizumab
Mechanism of action

Humanized IgE antibody reduces circulating IgE

87

Humanized IgE antibody reduces circulating IgE

Omalizumab
Mechanism of action

88

Omalizumab
Effects

Reduces frequency of asthma exacerbaration

89

Omalizumab
Clinical application

Severe asthma inadequatly controlled by other agents