Flashcards in Drugs Used In Asthma Deck (90):
0
Beta agonists
Albuterol
Salmeterol
Metaproterenol
Terbutaline
Formoterol
Epinephrine
Isoproterenol
1
Albuterol
Selective Beta2 agonist
2
Salmeterol
Selective Beta2 agonist
3
Metaproterenol
Selective Beta2 agonist
4
Terbutaline
Selective Beta2 agonist
5
Formoterol
Selective Beta2 agonist
6
Albuterol
Mechanism of action
Selective Beta2 agonist
7
Salmeterol
Mechanism of action
Selective Beta2 agonist
8
Albuterol
Effect
Prompt, efficacious bronchodilation
9
Prompt, efficacious bronchodilation
Albuterol
Effect
10
Salmeterol
Effects
Slow onset, primarily preventive action; potentiates corticosteroid effects
11
Slow onset, primarily preventive action; potentiates corticosteroid effects
Salmeterol
Effects
12
Albuterol
Clinical applications
Asthma
Chronic obstructive pulmonary disease (COPD)
Drug of choice in acute asthmatic bronchospasm
13
Asthma
Chronic obstructive pulmonary disease (COPD)
Drug of choice in acute asthmatic bronchospasm
Albuterol
Clinical applications
14
Salmeterol
Clinical applications
Asthma prophylaxis
15
Asthma prophylaxis
Salmeterol
Clinical applications
16
Albuterol
Toxicity
Tremor
Tachycardia
Overdose: arrhythmias
17
Tremor
Tachycardia
Overdose: arrhythmias
Albuterol
Salmeterol
Toxicity
18
Salmeterol
Toxicity
Tremor
Tachycardia
Overdose: arrhythmias
19
Epinephrine
Nonselective Alpha and Beta agonist
20
Nonselective Alpha and Beta agonist
Epinephrine
21
Epinephrine
Mechanism of action
Nonselective Alpha and Beta agonist
22
Epinephrine
Effects
Bronchodilation plus all other sympathomimetic effects on cardiovascular and other organ systems
23
Bronchodilation plus all other sympathomimetic effects on cardiovascular and other organ systems
Epinephrine
Effects
24
Epinephrine
Clinical applications
Anaphylaxis
Asthma
(Others)
Rarely used for asthma (Beta2-selective agents preferred)
25
Anaphylaxis
Asthma
(Others)
Rarely used for asthma (Beta2-selective agents preferred)
Epinephrine
Clinical applications
26
Isoproterenol
Beta1 and Beta2 agonist
27
Beta1 and Beta2 agonist
Isoproterenol
28
Isoproterenol
Mechanism of action
Beta1 and Beta2 agonist
29
Isoproterenol
Effects
Bronchodilation plus powerful cardiovascular effects
30
Bronchodilation plus powerful cardiovascular effects
Isoproterenol
Effects
31
Isoproterenol
Clinical applications
Asthma (but Beta2-selective agents preferred)
32
Asthma (but Beta2-selective agents preferred)
Isoproterenol
Clinical applications
33
Corticosteroids, inhaled
Fluticasone
Beclomethasone
Budesonide
Flunisolide
34
Fluticasone
Corticosteroid, inhaled
35
Beclomethasone
Corticosteroid, inhaled
36
Budesonide
Corticosteroid, inhaled
37
Flunisolide
Corticosteroid, inhaled
38
Corticosteroids, inhaled
Mechanism of action
Alters gene expression
39
Corticosteroids, inhaled
Mechanism of action
Alters gene expression
40
Alters gene expression
Corticosteroids, inhaled
Corticosteriods, systemic
Mechanism of action
41
Corticosteroids, systemic
Mechanism of action
Alters gene expression
42
Fluticasone
Mechanism of action
Alters gene expression
43
Budesonide
Mechanism of action
Alters gene expression
44
Beclomethasone
Mechanism of action
Alters gene expression
45
Corticosteriods, inhaled
Effects
Reduces mediators of inflammation
Powerful prophylaxis of exacerbations
46
Reduces mediators of inflammation
Powerful prophylaxis of exacerbations
Corticosteriods, systemic
Effects
47
Corticosteriods, systemic
Effects
Reduces mediators of inflammation
Powerful prophylaxis of exacerbations
48
Prednisone
Effects
Reduces mediators of inflammation
Powerful prophylaxis of exacerbations
49
Methylprednisolone
Effects
Reduces mediators of inflammation
Powerful prophylaxis of exacerbations
50
Betclomethasone
Effects
Reduces mediators of inflammation
Powerful prophylaxis of exacerbations
51
Budesonide
Effects
Reduces mediators of inflammation
Powerful prophylaxis of exacerbations
52
Corticosteroids, inhaled
Clinical applications
Asthma
Adjunct in COPD
Hay fever (nasal)
53
Asthma
Adjunct in COPD
Hay fever (nasal)
Corticosteroids, inhaled
Clinical applications
54
Corticosteroids, systemic
Clinical applications
Asthma
Adjunct in COPD
55
Asthma
Adjunct in COPD
Corticosteroids, systemic
Clinical applications
56
Corticosteroids
Fluticasone
Beclomethasone
Budesonide
Flunisolide
Prednisone
Methylprednisolone
57
Fluticasone
Beclomethasone
Budesonide
Flunisolide
Prednisone
Methylprednisolone
Corticosteroids
58
Stabilizers of mast and other cells
Cromolyn
Nedocromil
59
Cromolyn
Stabilizers of mast and other cells
60
Nedocromil
Stabilizers of mast and other cells
61
Nedocromil
Cromolyn
Mechanism of action
Alter function of delayed chloride channels
Inhibits inflammatory cell activation
62
Alter function of delayed chloride channels
Inhibits inflammatory cell activation
Nedocromil
Cromolyn
Mechanism of action
63
Nedocromil
Cromolyn
Effects
Prevents acute bronchospasm
64
Prevents acute bronchospasm
Nedocromil
Cromolyn
Effects
65
Nedocromil
Cromolyn
Clinical applications
Asthma
(other routes used for ocular, nasal ang GI allergy)
66
Asthma
(other routes used for ocular, nasal ang GI allergy)
Nedocromil
Cromolyn
Clinical applications
67
Methylxanthine
Theophylline
68
Theophylline
Methylxanthine
69
Theophylline
Mechanism of action
Uncertain
Phosphodiesterase inhibition
Adenosine receptor antagonist
70
Uncertain
Phosphodiesterase inhibition
Adenosine receptor antagonist
Theophylline
Mechanism of action
71
Theophylline
Effects
Bronchodilation
Cardiac stimulation
Increased skeletal muscle strength (diaphragm)
72
Bronchodilation
Cardiac stimulation
Increased skeletal muscle strength (diaphragm)
Theophylline
Effects
73
Theophylline
Clinical applications
Asthma
COPD
74
Asthma
COPD
Theophylline
Clinical applications
75
Leukotriene antagonists
Montelukast
Zafirlukast
76
Montelukast
Leukotriene antagonist
77
Zafirlukast
Leukotriene antagonist
78
Montelukast
Mechanism of action
Block leukotriene D4 receptors
79
Block leukotriene D4 receptors
Montelukast
Zafirlukast
Mechanism of action
80
Montelukast
Effects
Block airway response to exercise and antigen challange
81
Block airway response to exercise and antigen challange
Montelukast
Zafirlukast
Effects
82
Montelukast
Clinical applications
Prophylaxis of asthma especially in children and in aspirine-induced asthma
83
Prophylaxis of asthma especially in children and in aspirine-induced asthma
Montelukast
Zafirlukast
Clinical applications
84
IgE antibody
Omalizumab
85
Omalizumab
IgE antibody
86
Omalizumab
Mechanism of action
Humanized IgE antibody reduces circulating IgE
87
Humanized IgE antibody reduces circulating IgE
Omalizumab
Mechanism of action
88
Omalizumab
Effects
Reduces frequency of asthma exacerbaration
89