Interstitial Lung Disease Flashcards Preview

Y1 Respiratory > Interstitial Lung Disease > Flashcards

Flashcards in Interstitial Lung Disease Deck (28):
1

What are interstitial Lung Diseases?

any disease process that affects the Lung interstitium

2

Classic symptoms of ILD?

breathlessness
dry cough

3

Granulomatous, type IV hypersensitivity disease of unknown cause

Sarcoidosis

4

Common system involvement of Sarcoidosis

lungs, lymph nodes, joints, liver, skin, eyes

5

What type of granuloma is found in the lung of sarcoid patients?

non-caseating

6

Acute sarcoidosis is ____-_______

self-limiting

7

Symptoms of acute sarcoidosis

erythema nodosim
bilateral hilar lymphadenopathy
arthritis
UVeitis
Parotitis
Fever

8

signs of chronic sarcoidosis

lung infiltrates
skin infiltrates
peripheral lymphadenopathy
hypercalcaemia

9

DDx with Sarcoidosis

TB, lymphoma, carcinoma, fungal infection

10

Investigations where sarcoidosis is suspect

CXR
CT
Biopsy
Pulmonary function
Blood test

11

Expected sarcoidosis findings in CXR

Bihilar lymphadenopathy

12

Expected sarcoidosis findings in CT

peripheral nodular infiltrates

13

Expected sarcoidosis findings in biopsy

non-caseating granuloma if anything

14

Expected sarcoidosis findings in pulmonary function tests

restrictive defect
breathlessness
reduction in blood gas levels

15

Blood test results in sarcoidosis

raised ACE
raised Calcium
raised, LFTs, CRP, Kidney

16

Treatment for acute sarcoidosis

let it settle itself

17

treatment for chronic sarcoidosis

oral steroids
if vital organs affected, immunosuppression (azathioprine, methotrexate, anti-TNF)

18

Type III hypersensitivity reaction to antigen

Extrinsic allergic alveolitis - hypersensitivity pneumonitis

19

Acute symptoms of extrinsic allergic alveolitis

cough, breathless, fever, myalgia, +/- pyrexia, +/- crackles, hypoxia

20

time frame for extrinsic allergic alveolitis symptoms

several hours after exposure

21

CXR results for acute allergic alveolitis

widespread pulmonary infiltrates

22

Treatment for acute extrinsic allergic alveolitis

oxygen, steroid and antigen avoidance

23

Chronic alveolitis presents with _____

progressive breathlessness and a cough

24

Signs of chronic extrinsic allergic alveolitis

crackles, clubbing is unusual

25

CXR signs of chronic extrinsic allergic alveolitis

pulmonary fibrosis, mostly in the upper zones

26

PFT signs of chronic extrinsic allergic alveolitis

restrictive defect, low FEV1/FVC, high or normal ratio, low gas transfer

27

Diagnosis of extrinsic allergic alveolitis

history, exam, lung biopsy, ask about the pets

28

Treatment for chronic extrinsic allergic alveolitis

remove antigen exposure, oral steroids if breathless or low gas transfer