JVD 2020 #1 Diagnostic Yield of Micro-Computed Tomography (micro-CT) Versus Histopathology of a Canine Oral Fibrosarcoma; Reiter Flashcards
What is the potential advantage of micro-CT for biopsy?
Micro-CT delivers isotropic 3D image volumes without the necessity to cut and essentially destroy the sampled tissue; has been employed primary in clinical practice for diagnostic workup of rodents and rabbits
Can micro-CT be used alone for estimating the total volume of tumors and margins?
No, in the present case, it is most useful for complementing histopathology as histopath showed extension of tumor cells to the borders of sample.
What limited spatial resolution of the excised mass?
High resolution scans with true spatial resolutions in the range of 1-2mm can be achieved with specimens 2-4mm in diameter. It was not well suited for the diameters of several centimeters as the mass presented here.
What is Lugol’s iodine solution?
One of the most widely used contrast agents and proven to provide high contrast for diverse vertebrate tissues.
Other routine contrasts agents are compounds containing molybendum, tungesten, silver, gold and osmium.
Clinical image
Photo showign a canine oral fibrosarcoma at teh right upper jaw, centered around the R MX caninen tooth and extending to midline of the rostral hard palate.
