Lecture 2: Histology Flashcards Preview

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Flashcards in Lecture 2: Histology Deck (20):
1

Atypical synapse in which synapse is along the axon

En passant synapse

2

What does the neuromuscular junction contain?

Enlarged terminal with synaptic vesicles, enlarged cleft, and the muscle sole plate

3

Where do we find multipolar neurons?

Throughout the CNS

4

Where do we find bipolar neurons?

In the "special sensory" regions

5

Where do we find unipolar neurons?

In the sensory ganglia (DRG)

6

Star-shaped granule cells are called?

Stellate cells

7

Granule/stellate cells regulate

Regional information processing

8

What are three ways to classify a neuron based on its axon length?

Projection cells, interneurons, amacrine cells

9

T/F: Interneurons are generally excitatory

False. Interneurons remain within the region of a dendritic field and provide local synpatic interactions and feedback.

10

What are amacarine cells? Where are they primarily found?

Axon-less cells; retina and olfactory bulb

11

Three types of neuronal cell death

Necrosis, apoptosis, autophagy

12

What is different about microglial cell origins?

Derived from mesoderm, not ectoderm like astrocytes and oligodendrocytes

13

Broadly, microglia are the...

Resident macrophages of the CNS

14

Microglia can exist in resting states and active states. What are the two active states?

Non-phagocytic microglia (immediately responsive) and phagocytic microglia (apoptose neurons during development and respond to trauma)

15

What are the five main functions of astrocytes?

Structural/metabolic support, scaffolding during development, regulate ions/extracellular molecules, blood-brain barrier, CNS scars

16

Astrocytomas make up __% of primary brain tumors. What is the most common? Describe.

50%; Glioblastoma multiforme: fast-growing tumor cells surrounding necrotic region called pseudopalisading necrosis

17

What are the two histological characteristics of oligodendrogliomas?

"Fried egg" cells and "chicken wire" capillaries

18

What are tumors of ependymal cells called?

Ependymomas

19

What characterizes ependymomas?

Pseudorosettes

20

What are tumors of Schwann cells called? Describe.

Schwannomas; typically encapsulated and benign

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