Lecture 23: The Synapse Flashcards Preview

HUBS 191💃✨ > Lecture 23: The Synapse > Flashcards

Flashcards in Lecture 23: The Synapse Deck (11):
1

Can there be multiple action potentials in one neuron?

- Yes

2

An analogy for an action potential moving down the axon....

- A Mexican wave

3

What is a synapse?

- The junction between nerve cells, where a nerve impulse is transferred from one neuron to another

4

What are some features of the electrical synapses?

- Small gap between two neurons
- Connected by tight junctions and form a tunnel
- PHYSICAL DIRECT CONNECTION
- Direct propagation of Action Potential
- V FAST synapse

5

What are some features of the chemical synapses?

- Synaptic cleft
- Physical gap
- Neurotransmitters
- Indirect propagation of Action Potential
- Slower than electric synapses

6

What are the two different types of synapses?

- Electrical
- Chemical

7

Nerve to muscle synapse is called the....

- Neuromuscular junction

8

What are the key components of the chemical synapse?

- Presynaptic cell 'output zone'
- Synaptic knob
- Synaptic cleft
- Postsynaptic cell 'input zone' (voltage gated Na+ K+, stimulus gated Na+)
- Voltage gated Ca2+ channels
- Vesicles w/ Neurotransmitters
- Cytoskeleton
- Mitochondria (responsible for production of ATP)

9

What is the importance of Calcium?

- Important for bones and the nervous system
- Triggers the release of vesicles
- VERY low concentrations intracellularly

10

How is the signal transmitted?

- Neurotransmitter diffuses across synaptic cleft to reach postsynaptic membrane
- Binds to specific receptors
- If Na+ channels are open depolarisation in postsynaptic cell occurs (initiate things)
- If K+ channels open then repolarisation occurs
- If neurotransmitters bid to Cl- channels then hyperpolarisation occurs (shuts things down)

11

In signal transmission what happens if depolarisation is going on?

- An excitatory signal