Flashcards in Liver Enzymes & Dx Deck (28):
AST and ALT are enzymes found where?
Ferroxidase and proteases are enzymes found where?
Where is glutamate dehydrogenase found?
What was the older view of liver cell death?
What is the newer view of liver cell death?
bleb formation (mild)
hepatocyte apoptosis sequence?
What liver enzymes are in membrane?
What liver enzymes are in cytoplasm
What liver enzymes are in mitochondria?
is ALT of AST more liver specific? why?
there is mAST in every cell that has mitochondria
AST>ALT means what?
acute, affecting mitochondria
ALT>AST means what?
Why is AST removed faster than ALT?
AST smaller 36vs. 18 hours
What other viruses can cause hepatitis besides Hep A-E?
ALT levels for mild, moderate, severe Hep A infection?
why is ALT elevated in the first place? Viruses don't want to kill hepatocytes
Immune system CD8s apoptosing everything!!
Acute Hep A ALT levels are what?
Acute Hep B ALT core IgM levels what what?
Chronic Hep B and C ALT surface Ag levels are what?
Number one and two drug induced liver disease is?
4 drugs/toxins for hepatitis
2 enzymes involved in biliary disease?
What is GGT important for?
2 kinds of biliary obstruction, they are? what are the GGT and ALP levels?
extrahepatic +++ GGT, ALP
intrahepatic +GGT, ALP
correlation between alcohol and GGT induction?
What is the most common enzyme elevated?
what a huge risk factor for raised ALT/GGT?