LIVER FUNCTION TEST part 1 Flashcards

(33 cards)

1
Q

What organ is the largest and most versatile organ in the body?

A

Liver

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2
Q

What is the weight of liver?

A

1.5 - 1.2 kg

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3
Q

What separates the two loves in the liver?

A

Falciform ligaments

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4
Q

carries blood from alimentary tract

A

Portal vein

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5
Q

carries oxygenated blood to the liver

A

Hepatic artery

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6
Q

What is the composition of Liver?

A

Lobules demarcated by CT septa and
vascular & biliary vessels

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7
Q

It is found in the center of the lobule and Parenchymal epithelial cells radiate from the vein.

A

Central Hepatic Vein

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8
Q

blood-carrying vascular channels on either side of the liver cell plates

A

Sinusoids

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9
Q

either endothelial cells or Kupffer cells

A

Lining cells

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10
Q

It is the largest group of fixed macrophages

A

endothelial cells or Kupffer cells

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11
Q

 tissue space between the endothelial cells & hepatocytes

A

Spice of Disse

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12
Q

What fills the Space of Disse?

A

Interstitial fluid

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13
Q

What is the function of Spice of Disse?

A

It transfer nutrients and waste products from blood occurs

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14
Q

 polygonal cells that constitute ~ 60% of the liver mass

A

Hepatocytes

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15
Q

What are the specialized surface of the cell?

A

 Sinusoidal surface
 Intercellular surface
 Canalicular surface

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16
Q

TRUE OR FALSE:
Hepatic parenchymal cells have a underdeveloped organellar substructure.

A

FALSE ; developed

17
Q

energy generation

18
Q

What is the other name of Lysosomes?

A

Hydrolytic enzymes

19
Q

degradative functions

20
Q

site of many functions: drug metabolism & bile acid SYNTHESIS

A

Endoplasmic reticulum

21
Q

tubules & vesicles

22
Q

This organ function as: bilirubin conjugation, drug detoxification & cholesterol synthesis

23
Q

lamellar profile with ribosomes

24
Q

 synthesis of specific proteins (e.g. albumin, coagulation factors)

25
It functions as the "packaging process" of the cell
Golgi complex
26
produces lipoproteins (VLDL) ; Glycoprotein synthesis
Golgi Complex
27
maintain cell shape and provide contractile force
Microtubules and Microfilaments
28
Receives, processes & stores materials absorbed from the digestive tract
Microtubules and Microfilaments
29
What are the materials that are absorbed and stored from the DT?
 amino acids  CHO  fatty acids  cholesterol
30
multiple plasma proteins
Synthesis
31
Main organ of detoxification Major site of catabolism of hormones
Microtubules and Microfilaments
32
These tests are done for liver function test
test for the proteins, bilirubin, ammonia and enzymes (ALT,AST, GTT, AGPT, SGOT)
33
What are the factors to be considered in doing Liver Function Tests?
Sensitivity Specificity Selectivity