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Flashcards in Male fertility Deck (10):
1

normal FSH indicates no significant _____ dysfunction

testicular

2

if sterile patient negative for CFTR/5T, then .. (testing)

renal U/S

3

why test estradiol?

T > estradiol via aromatase

 

high levels of aromatase in body fat

3

inheritance patern for CBAVD

most autosomal recessive

3

common defects when CFTR testing is negative

 

pathophys is these cases

renal abnormalities

 

mesonephric duct gives rise to uretal bud, SV, vas deferens, lower 2/3 of epididymus

defect in mesonephic duct early leads to agenesis of genital ducts and ipsilateral kidney

5

if low T, then.... (testing)

repeat T earlyi n AM

order LH, prolactin estradiol

6

common mutation pattern in CBAVD an cystic fibrosis patients

 

impact of mutations

most have 2 mutations

second most oftenon 5T alllele

 

casue involution of genital ducts during embryogenesis

spermatogenesis is fine

8

___d stem cell > spermatozoa

 

____days transit in epididymis

 

= ___d to reflect change in SA

70 days stem cell to spermatoza

20days transit epididymis

90 days to reflect change

9

most common cause of male infertility

 

examples

testicular

 

(varicoceles, gondatoxins, primary testicular problems)

10

initital evaluation of infertile male

Full H+P

Sereum analysis (>3)

Hormones (Total T, FSH, reserve LH, estradiol, prolactin if low T)

scrotal U/S if testicular gross abnl