Male Repro Histology Flashcards Preview

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Flashcards in Male Repro Histology Deck (50):
1

mesonephric ducts

male- wolffian ducts

2

paramesonephric ducts

female- mullarian ducts

3

cloacal folds and genital tubercle

external genitalia

4

testis septa

divides into lobules

5

testis mediastinum

posterior thickening

6

spermatogenesis

meiotic division + spermiogenesis

7

spermiogenesis

maturation of spermatids into spermatozoa

8

spermatagonia type Ad

undergo mitosis

9

spermatagonia type Ap

undergo mitosis, but are closer to starting meiosis

10

spermatogonia type B

meiosis

11

progression of spermatogonia

spermatogonia--> primary spermatocyte--> secondary spermatocyte--> spermatids-> spermatozoa

12

spermatagonia

small cells with pale nucleus
found along basal lamina
2 copies of diploid genome

13

primary spermacyte

large cells with chromosome coiling
will be most of cells present
2 copies of diploid genome

14

secondary spermatocyte

smaller, not usually seen
1 copy of diploid genome

15

early spermatid

small, condensed chromatin
close to the lumen
1 copy of haploid genome

16

late spermatid

lost cytoplasm, developed a flagellum, condensed nucleus
heads in stroll cells and tails in lumen
1 copy of haploid genome

17

3 phases of spermatogenesis and significant event in each

golgi phase- acrosomal granule is formed, flagellum starts to form
acrosomal phase- acrosomal cap formed over nucleus, flagellum elongates, nucleus condenses
maturation- extra cytoplasm shed, spermatozoa released into seminiferous tubule lumen

18

parts of the spermatozoa

head- nucleus with acrosome
neck- centriole location
tail- complicated

19

parts of the tail of a spermatozoa

midpiece- axoneme, mitochondria, outer dense fibers
principal- axoneme, outer dense fibers, circular fibers
tail- axoneme

20

axoneme

microtubules surrounded by proteins that form the flagellum

21

significant feature of sertoli cells

prominent nucleolus

22

secretions of sertoli cells and their roles

androgen binding protein- binds androgens
inhibin/activin- control spermatogenesis
AMH- promotes mullarian duct regression

23

blood testis barrier

sertoli cells connected by zonula occludins

24

cells in the interstitium of testis

myoid cells- contractile function to push spermatozoa out of seminiferous tubules
interstitial cells of leydig- secrete testosterone

25

roles of testosterone throughout life

8-18wks fetal- mesonephric duct development
- converted to DHT for external genitalia development
puberty- spermatogenesis, libido, secondary sex characterstics, function of accessory glands

26

path of spermatozoa after leaving seminerferous tubules

straight tubules--> rete testis--> efferent ducts

27

function of efferent ducts

transport spermatozoa

28

sperm storage site

tail of epididymis

29

lining of duct system

rete testis- simple cuboidal with cilia/microvili
efferent ducts- pseudostratified columnar with cilia or cuboidal

30

lining of epididymis

pseudo stratified columnar- height decreases distally

31

decapacitation

addition of a glycoprotein coat to spermatozoa in the epididymis to prevent immunological attack

32

where do sperm gain motility

epididymis

33

path of ductus deferens

up from epididymis, through inguinal canal, passes posteriorly to urinary bladder and meets with seminal vesicle duct to form ejaculatory duct

34

what is in seminal vesicle secretions

sugars, amino acids, prostaglandins, coagulation proteins

35

appearance of ductus deferens

3 layers of smooth muscle
thick walled smaller lumen
lined with pseudo stratified columnar

36

compartments and contents of the blood testis barrier

basal- spermatogonia and primary spermocytes
adluminal- everything else

37

clinical zones of prostate- what are they for?

periurethral zone- around urethra
central zone- outside periurethral zone
transitional-
peripheral
describing tumor location- peripheral ones have to be big to affect the urethra

38

corpora amylacea

accumulation of fluids in the prostate

39

what does the prostate secrete

alkaline fluid to neutralize the vagina
PSA
citric acid
fibrinolysin

40

marker of prostatic cancer

prostatic specific antigen- spills over into blood with prostatic cancer

41

sympathetic innervation to ______ causes ejaculation

epididymis, ductus deferns, seminal vesicle, prostate gland

42

what is released from bulbourethral glands

pre-ejaculatory fluid into the penile urethra to prep it for spermatozoa

43

arousal is from

parasympathetic simulation via dorsal nerve of the penis releasing NO which results in dilation of the helicine arteries and relaxation of vascular sinuses

44

orchitis

inflamation of the testis caused by infection

45

granulomatosus orchitis

testicular inflammation caused by trauma with proliferation of capillaries and immune cells

46

torsion

twisting of spermatic cord, cutting off blood supply to the testicals

47

testicular cancer types

seminoas- from spermatogenic cells
non- seminoas- from elsewhere

48

benign prostatic hypertrophy

glandular cell hypertrophy caused by DHT conversion in stream cells

49

adenocarcinoma of prostate

from glandular cells of the prostate
usually in peripheral zone

50

squamous cell carcinoma of penis

usually in glans or prepuce