Male Reproductive Histology Lab

Question 1

Pale staining cells with a prominent nucleus

Answer 1

Sertoli cell

Question 2

Cells on basement membrane; mitotic derivatives of primordial germ cells

Answer 2

Spermatogonia

Question 3

pronounced prophase nucleus, round distinct chromatin profile

Answer 3

primary spermatocyte

Question 4

In underlying connective tissue adjacent to Sertoli cells –> pale staining cells with eosinophilic cytoplasm

Answer 4

Leydig cells

Question 5

plexus of testicular veins that traverse the spermatic cord

Answer 5

pampiniform plexus

Question 6

“hill” in the posterior prostate that marks the site of the entrance of the ejaculatory ducts

Answer 6

seminal colliculus/verumontanum

Question 7

support cells for spermatogonia and progeny (see below); somatic cells and do not divide after puberty (10% of cells in tubules post puberty)

Answer 7

sertoli cells

Question 8

become mitotically and meiotically active at puberty and then comprise 90% of cells in tubules

Answer 8

germ cells

Question 9

2d, 2n

Answer 9

spermatogonia

Question 10

4d, 2n

Answer 10

Primary spermatocytes

Question 11

2d, 1n

Answer 11

Secondary spermatocytes

Question 12

1d, 1n

Answer 12

Spermatids and Spermatozoa

Question 13

cuboidal epithelium that conducts immature spermatozoa from seminiferous tubules to epididymis

Answer 13

rete testis

Question 14

produce testosterone under stimulation of LH in late fetal and postnatal state (stimulated by HCG in the placenta)

Answer 14

leydig cells

Question 15

Leydig cells produce testosterone under the influence of ______

Answer 15

luteinizing hormone

Question 16

Luteinizing hormone is stimulated by _____ in the early fetus

Answer 16

HCG

Question 17

Prenatally, ______ suppresses LH production

Answer 17

testosterone

Question 18

Why don’t any new antigens created in the course of sperm maturation provoke
immune reactions in the mother?

Answer 18

Primary spermatocytes and beyond live within sertoli tight junctions on the bloodless side of the blood-testis barrier

Question 19

T/F The progeny of a given type A pale

spermatogonium are clonal

Answer 19

T –> and remain connected to each other by bridges of cytoplasm until late in development

Question 20

lined by pseudostratified low columnar epithelium, some with microvilli, which resorb fluid, and some with sparse cilia that help propel the (as yet) non-motile spermatozoa from seminiferous tubules to ductus epididymis

Answer 20

efferent ductules

Question 21

lined by tall pseudostratified columnar epithelium with large branched stereocilia [not true cilia as lack microtubules and basal body]). These cells with stereocilia (also known as
principle cells), reabsorb much of the fluid from the lumen, as well as secreting additional components into the luminal fluid.

Answer 21

epididymis

Question 22

Site of maturation of spermatozoa and where they acquire motility

Answer 22

epididymis

Question 23

Most prostatic adenocarcinomas arise from glands in the _____ zone

Answer 23

peripheral

Question 24

Most male urethral obstruction caused by benign overgrowth of glands/stroma in the _____ and _____ zones

Answer 24

transitional and periurethral

Question 25

Lined by urothelium (transitional epithelium) until very close to penile tip, where stratified squamous mucosa

Answer 25

urethra

Question 26

accessory male genital glands

Answer 26

seminal vesicles, prostate gland, and bulbourethral glands