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Treatment of Male/Female Sex Dysfunction Flashcards

(23 cards)

1
Q

3 components of male sexual dysfunction

A

loss of libido, impotence, ejaculatory failure

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2
Q

neural control of male sexual function

A

forebrain limbic system + circulating androgens

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3
Q

failure to attain an erection of sufficient strength to carry out sexual intercourse 25% of hte time

A

impotence

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4
Q

Central erection sequence involves wbhat effects on ps/sympathetic system

A

increase in ps and inhibition of sympathetic

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5
Q

local parasympathetic reflex arc

A

penis-spinal cord-penis

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6
Q

Relaxation of the ____ arteries and the smooth muscle of the ____ in the _____ increase penile blood flow

A

helicine arteries and smooth muscel of trabeculae of corpus cavernosa

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7
Q

T/F venous drainage from penis is impeded by compression by engorged corpora cavernosa

A

T

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8
Q

___ efferents are involved in ejaculation

A

sacral efferents

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9
Q

Changes in blood flow during erection are mediated by release of ___ from post synaptic ps neurons and endothelial cells

A

nitrous oxide

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10
Q

Readily diffusible NO stimulates ___ in the trabecular and arterial smooth muscle cells increasing their content of ____ which in turn relaxes the cells

A

guanylate cyclase –> cyclic GMP

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11
Q

Dx of erectile dysfunction

A

exclusion, pt complaint, bulbocavernosus reflex test, npt testing, intracorporeal injection of vasodilators, ultrasound or MRA

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12
Q

T/F tumescence correlates with REM sleep

A

T –>16-20 times

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13
Q

Tx of male sexual dysfunction

A

counseling, surgery,iatrogenic drug adjustment, testosterone, vacuum, penile implants, vasodilators

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14
Q

Vasodilators for erectile dysfunction

A

papaverine, PGE1 analog alprostadil, suppository of alprostadil, oral PDE5 inhibitors (viagra)

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15
Q

PDE5 inhibitors

A

cgmp phosphodiesterase inhibitors act by inhibiting breakdown of cGMP by PDE –> maintains vasodilatory response

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16
Q

PDE5I are metabolised by ____ to an active/inactive metabolite

A

CYP3A4 to active metabolite

17
Q

T/F PDE5I have quick action

18
Q

Side effect of PDE5I

A

sperm motility, vaginal smooth muscle, esophageal motility, color vision in retina, inhibition of platelet aggregation, vasodilation of other vascular beds

19
Q

PDE5I should not be taken within 5 hours of taking a ____

20
Q

APA definition of female sexual dysfunction

A

lack of arousal, pain, and anorgasmia

21
Q

T/F female sexual dysfunction has greater prevalence among postmenopausal women

22
Q

3 etiological theories of female sexual dysfunction

A

vascular, hormone, and dissatisfaction theories

23
Q

Tx of female sexual dysfunction

A

educational, ERT, PDE5I (only works on those with SSRI induced dysfunction), eros therapy, topical tx