micro p132-141 Flashcards Preview

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Flashcards in micro p132-141 Deck (33):
1

anthrax capsule is made of

polypeptide capsule (D-glutamate)

2

what is the preformed toxin produced by Baciluus cereus?

cereulide

3

bug associated with granulomatosis infantiseptica and neonatal meningitis?

Listeria monocytogenes

4

what is unique about Listeria as a gram positive organ?

only gram positive organism to produce endotoxin

5

what organism give you TB like symptoms and get stained similar to TB?

Nocardia

6

what is the treatment for Nocardia?

sulfonamide

7

which TB test has fewer false positives from BCG vaccination?

Interferon gamma release assay

8

what are the 2 roles of cord factor from TB?

1. inhibits macrophage maturation
2. induces release of TNF-alpha

9

In TB, what inhibit phagolysosomal fusion?

sulfatides (surface glycolipids)

10

what path is associated with infection of skin and superficial nerves that lead to "glove and stocking" loss of sensation?

Leprosy (Hansen dz)

11

which type of leprosy is associated with low cell mediated immunity?

Lepromatous

12

which type of leprosy is associated with cell mediated immunity?

Tuberculoid

13

what type of immune response is upregulated in Lepromatous leprosy?

humoral Th2 response

14

what type of immune response is upregulated in Tuberculoid leprosy?

cell mediated immunity with Th1 type immune response

15

treatments for leprosy?

1. dapson, rifampin for Tuberculoid form
2. clofazimine is added for Lepromatous form

16

where is actinomyces found?

normal oral flora

17

explain how Nocardia can infect immunecompromised/immunecompetent person?

Nocardia causes pulmonary infections in immunocompromised and cutaneous infections after trauma in immunocompetent

18

what enzyme breaks down lactose into glucose and galactose?

Beta galactosidase

19

what agar would you use for lactose fermenters to grow as purple/black colonies?

EMB agar

20

how would you distinguish EHEC from other E. coli?

EHEC does not ferment sorbitol

21

name three gram negative bugs that are lactose nonfermenter and produce H2S?

salmonella, proteus, yersinia

22

what bug does not produce H2S and is lactose nonfermenter?

shigella

23

what agar is used to test H2S production?

TSI agar

24

what bug is oxidase positive and also lactose nonfermenter?

Pseudomonas

25

name all the oxidase neg, lactose nonfermenter?

salmonella, proteus, yersinia, shigella

26

name all the lactose fermenter in gram neg?

klebsiella, E. coli, enterobacter, citrobacter, serratia

27

how will the lactose fermenter show on MacConkey agar?

pick colonies

28

name of the path that is rapidly progressive and has necrotic cutaneous lesion typically seen in immune compromised pts?

Ecthyma gangrenosum

29

what bug is associated with "pseudoappendicitis?"

Yersinia enterocolitica

30

what is the name of the tick that causes Lyme dz?

Ixodes deer tick

31

Ixodes deer tick is also a vector for what bug?

Anaplasma spp. and protozoa Babesia

32

what is the natural reservoir for Lyme dz?

mouse

33

what bug can be visualized by aniline dyes?

Borrelia