Microbiology--Mycology/Parisitology Flashcards Preview

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Flashcards in Microbiology--Mycology/Parisitology Deck (40):
1

Mississipi and Ohio River valleys

Histoplasmosis--macrophage filled with histoplasma; bird/bat droppings

2

East of mississippi river and central america

blastomycosis; broad based budding; granulomatous nodules

3

Southwestern US, California

Coccidioiodmycosis--erythema nodosum, arthralgias, pneumonia, meningitis

4

Latin America

Paracoccidioidomycosis--buddying yeast with captains wheel formation

5

melanocyte damage causing hypopigmented/hyperpigmented patches; spaghetti and meatball appearance

Tinea versicolor (malassezia spp)--degrades lipids producing acids that cause damage

6

septate hyphae that branch at 45 degree angle

aspergillus fumigatus--acute angles--some spp produce aflatoxins which are associated with HCC

7

found in soid, pigeon droppings

cryptococcus neoformans--grown on Sabouraud agar, stains with india ink (halos) or mucicarmine; latex agglutination test detects polysaccharide capsular antigen is more specific

8

soap bubble lesions in the brain

cryptococcus neoformans

9

irregular, broad, nonseptate hyphae branching at wide angles

mucor/rhizopus--seen in ketoacidotic diabetic/leukemic patients; fungi proliferate in blood vessel walls, penetrate cribiform plate, enter brain; black necrotic eschar on fase;

10

dimorphic yeast, pseudohyphae/budding yeasts at 20 C; germ tubes at 37 C

candida albicans

11

disc shaped yeast on methenamine silver stain of lung tissue

pneumocystis jirovecii--prophylaxis when CD4 count drops below 200

12

local pustule with ascending lymphangiitis after rose thorn prick

Sporothrix schenckii--dimorphic cigar shaped budding yeast that lives on vegetation

13

bloating, flatulence, foul smelling fatty diarrhea (campers/hikers)

giardia lamblia--look for trophozoites/cysts in stool

14

bloody diarrhea, liver abscess, RUQ pain

entamoeba histolytica--serology or stool--cysts/RBCs/nuclei in parasite

15

severe diarrhea in aids patients, oocytes on acid fast stain

cryptosporidum

16

ring enhancing brain lesion in HIV patient

toxoplasma gondii

17

chorioretinitis, hydrocephalus, intracranial calcifications in infant

congenital toxoplasma infection

18

rapidly fatal meningoencephalitis after swimming in freshwater lake

naegleria fowleri--amoeba in spinal fluid that enters via cribiform plate

19

enlarged lymph nodes, recurring fever, somnolence, coma

Trypanosoma brucei--african sleeping sickness, tsetse fly; tx with suramin for blood borne disease or melarsoprol for CNS penetration

20

fevers 48 hrs apart

Plasmodium vivax/ovale--dormant form in liver

21

severe irregular fever patterns; brain/kidney/lung involvement

Plasmodium falciparum--parasitized RBCs occlude capillaries

22

72 hr cycle

Plasmodium malariae

23

fever and hemolytic anemia in Northeast US

babesiosis via tick; on blood smear will see ring form and maltese cross form; trx with atovaquone + azithromycin

24

dilated cardiomyopathy; megacolon; megaesophagus

Chagas disease via trypanosoma cruzi--South America; kissing bug transmits; tx with bensnidazole or nifurtinox

25

spiking fevers, hepatosplenomegaly, pancytopenia

Leishmaniasis: leishmania donovani via sandfly; macrophages containing amastigotes

26

foul green smelling discharge from vagina; itching and burning

trichomonas vaginalis--cannot exist outside human; seen on wetmount, strawberry cervix; metronidazole

27

intestinal infection with anal pruritus

enterobius vermicularis (pinworm); tx with bendazoles or pyrantel

28

intestinal infection causing vomiting, diarrhea, epigastric pain

strongyloides stercoralis--ivermectin or albendazole

29

intestinal infection causing anemia by sucking blood from inestinal walls

ancylostoma duodenale, necator americanus (hookworms)--bendazoles or pyrantel pamoate

30

hyperpigmented skin and river blindness; black skin nodules

onchocerca volvulus-ivermectin; blackfly, black skin nodules, black sight

31

Swelling in skin, worm in conjunctiva

loa loa via fly--diethylcarbamazine

32

blocks lymphatic vessels causing elephantiasis

wuchereria bancrofti--takes 1 yr after bite to see symptoms--diethylcarbamazine

33

Nematode routes of infection:

get sick if you EAT these: enterobius, ascaris, toxocara; get into your feed from the SANd: strongyloides, ancylostoma, necator; lay LOW to avoid bites: loa loa, onchocerca volvulus, wuchereria bancrofti

34

ingestion of larvae in undercooked pork

taenia solum--intestinal infection--praziquantel

35

ingestion of eggs in undercooked pork

cysticerosis, neurocysticercosis--praziquantel, albendazole for neuro

36

ingestion of larvae from freshwater fish

diphyllobothrium latum--vitamin B12 deficiency (tapeworm competes for B12)-->anemia; praziquantel

37

ingestion of eggs from dog feces

eichinococcus granulosus--hyatid cysts in liver that cause anaphylaxis if antigens released--albendazole

38

chronic infection can lead to SCC of bladder

schistosoma (fluke); snails are host; praziquantel

39

undercooked fish; biliary tract inflammation gallstones, cholangiocarcinoma

clonorchis sinensis--praziquantel

40

portal hypertension

schistosoma mansoni/japonicum