Module 7: Hypersensitivities Flashcards Preview

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Flashcards in Module 7: Hypersensitivities Deck (8)
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1

Hypersensitivity

disorders caused by an exaggerated or inappropriate immune response

2

Type I

Immediate

IgE Ab and mediators
Allergic reactions

3

Type II

Cytotoxic

Other Ab (not IgE)
Cytotoxic damage to tissues

4

Type III

Immune complex

SOLUBLE antigens form complexes with antibodies
Antigen-Ab complexes deposit in blood vessels and tissues leading to injury

5

Type IV

Delayed

No Ab involved
T lymph activity results in tissue damage

6

erythema

redness of skin due to congestion of the capillaries

7

induration

hardening

8

granuloma

tumor like mass or nodule formed due to chronic inflammation