Muscles II: Microscopic Anatomy/Sarcomere Flashcards

(48 cards)

1
Q

components of muscle fiber

A

sarcolemma, sarcoplasm, sarcoplasmic reticulum

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2
Q

two main structures unique to muscle fibers

A

t-tubules, sarcoplasmic reticulum

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3
Q

t-tubules

A

deep invaginations of the sarcolemma that extend into the sarcoplasm

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4
Q

t-tubules purpose

A

carry impulses from sarcolemma to help stimulate contraction. bring sarcolemma close to sarcoplasmic reticulum and all regions of the cell

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5
Q

where do t-tubules open to?

A

the outside of the muscle fiber

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6
Q

do t-tubules contain extracellular fluid?

A

yes

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7
Q

sarcoplasmic reticulum

A

internal membrane complex

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8
Q

purpose of sarcoplasmic reticulum

A

stores calcium used to initiate contraction

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9
Q

cisternae of sarcoplasmic reticulum

A

enlargend portion of calcium storage that released calcium when action potential travels down the transverse tubules eliciting muscle contraction

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10
Q

triad

A

structure made up of two terminal cristae and one t-tubule

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11
Q

purpose of triad

A

link between sarcolemma and sacroplasmic reticulum at all regions to have synchronous release of calcium (allows muscles to contract forcefully)

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12
Q

myofibrils

A

cylindrical structure within the muscle fibers that run the length of the cell

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13
Q

myofilaments

A

strands of protein that allow for contraction

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14
Q

2 types of myofilaments

A

thin, thick filaments

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15
Q

thick filaments are composed of

A

myosin

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16
Q

myosin 2 strands

A

intertwined tails and globular head

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17
Q

what do heads of the myosin form?

A

cross bridges

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18
Q

myosin contain binding site for

A

actin, ATP binding

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19
Q

thin filaments extend toward ____ of thick filament, heads extend ______ toward thin filament

A

middle, outward

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20
Q

thin filaments composed of

A

2 f-actin twisted around each other (filamentous)

21
Q

g-actin shape

22
Q

each actin strand is made of

A

g-actin (globular)

23
Q

2 regulatory proteins that are part of the thin filament

A

tropomyosin, troponin

24
Q

tropomyosin

A

threadlike protein covering part of actin

25
troponin
attaches to actin and tropomyosin and can bind calcium
26
sarcomere regions
M line, A band, H zone, I band
27
M line
line of protein that anchors to thick filaments/myosin filaments
28
A band
everywhere thick filaments occur
29
H zone
where thick filaments and no thin filaments
30
I band
only thin filaments around Z disc
31
sarcomere
overlapping thick and thin filaments forming the structural ad functional units within a myofibril
32
one sarcomere spans from one _____ to the next
z-line/disc
33
z-discs
specialized proteins perpendicular to the myofilaments and anchor thin filaments
34
what parts of the muscle shorten as the two sides come closer?
sarcomere, myofibril, muscle fibers
35
z line ncontraction change
move closer together
36
m line contraction change
remains stable
37
why does the m line remain stable during contraction?
actin is being pulled on by myosin
38
H zone contraction change
gets narrower
39
I zone contraction change
gets narrower
40
what led to the sliding filament theory of muscle contraction?
electron microscopy
41
sliding filament theory
muscles contract when sarcomeres shorten and muscle fibers slide past each other
42
M line cross section
thick filaments and accessory proteins anchored to them
43
H zone cross section
only thick filaments made of myosin
44
A band cross section
thick filaments and thin filaments interspersed
45
I band cross section
only thin filaments supporting proteins
46
eg of supporting proteins
connectin
47
connectin purpose
helps align thick and thin filaments within sarcomere
48
z-disc cross section
thin filaments and accessory proteins anchoring the thin filaments to the z-disc