Flashcards in Nervous system PHARM Deck (27)
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1
AChE inhibitors: indirect cholinergic agonists
increasing acetylcholine
ANTI ALZHEIMERS
2
DONEPEZIL : AChE inhibitor
dementia symptom control`
3
RIVASTIGMINE : AChE inhibitor
parkinsons AND dementia
4
MEMANTINE
**blocks NMDA-type glutamate receptors
*modest effect on moderate to severe alzheimers
*slows down nerve cell loss
5
dopamine precursors
levocopa-carbodopa
6
dopamine agonists - bind to dopamine receptors
BROMOCRIPTINE
PRAMIPEXOLE
7
BROMOCRIPTINE
dopamine agonist also acts on pituitary gland
**can cause pulmonary fibrosis**
8
PRAMIPEXOLE
can be used in cojmbo with levodopa
9
ANTICHOLINERG for parkinsons
benztropine :
use diphenhydramine if cants use benztropine
10
SCOPOLAMINE
anticholinergic
muscle problems
motion sickness
11
AMANTADINE
parkinsons - NMDA glutamate receptor antagonist (LIKE MEMANTINE-alzheimers)
levodopa induced dyskinesia LATE IN DISEASE
can exacerbate mental illness
12
muscle spasticity in MS
botulinum toxin
baclofen (taper off if discontinuing)
tizanidine
13
immune modulator for MS RELAPSING FORM
GLATIRAMER ACETATE
-L-GLUTAMINE, LYSINE, ARGININE
*PREG B
14
FINGOLIMOD
MS RELAPSING FORM
do not use with class I (NA+)or III (K+) antiarrythmias
15
LAMOTRIGINE
epilepsy and bipolar I
SE: serious skin rash
suicidal behavior and ideation
16
TOPIRAMATE
EPILEPSY AND MIGRAINES
suicidal behavior and ideation
unexplained death in epilepsy
**lots of probs
PREG D: DONT! !!
17
VALPROATE (merci)
epilepsy, mania, migraine
suicidal behavior
birth defects
18
HALOPERIDOL AND PROCHLORPERAZINE
CLASSICAL ANTIPSYCHOTICS
PROCHLOROPERAZINE (USED MORE FOR VOMITING)
C/I IN PARKINSONS
19
CLONODINE
A2
20
PHENTERMINE
FASTIN :WEIGHT LOSS
AUGMENT DOPAMINE
PREG CATEGORY X
21
ZOLPIDEM
AMBIEN
PERFORM COMPLEX NATURAL BEHAVIORS
22
SUMATRIPTAN
MIGRAINE RELIEF
23
BOTULINUM TOXIN
OVERACTIVE BLADDER, CHRONIC MIGRAINE
SPASTICITY
CAN GET PARALYSIS IN OTHER AREAS
24
ANTI-SEIZURE
CARBAMAZEPINE
PHENYTOIN: can cause
25
PHENYLZINE: MAOI
* ONLY USE WHEN OTHER ANTIDEPRESSANTS HAVE FAILED
**CAN CAUSE TYRAMINE TOXICITY
DON'T EAT CHOCOLATE / COFFEE
26
MODANAFIL
get in the mode: dont fall asleep: anti narcopleptic
27
