Flashcards in Herb-Drug Interactions Deck (45)
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1
What herb interacts with PPIs and why?
Achillea millefolium, Arctium lappa, Artemisia absinthium/vulgaris, Berberis aquifolium/vulgaris, Coleus, Cynara
D/t bitter properties and stimulation of HCl in the gut
2
What herbs can decrease drug absorption d/t increasing GI motility?
Achillea millefolium, Aloe vera latex, Arctium lappa, Artemisia absinthium/vulgaris, Berberis aquifolium/vulgaris, Cassia, Cynara
3
What herbs are contraindicated when combined with HRT can lead to estrogen excess?
Actaea racemosa (black cohosh), ***
4
What herb can decrease hot flashes caused by Tamoxifen?
Actaea racemosa
5
What herb(s) can cause hypoglycemic effects when combined with oral hypoglycemic meds (i.e. Metformin, Glyburide, Rosiglitazone, Insulin)?
Allium cepa/sativum, Aloe vera gel (internally), Arctium lappa, Artemisia vulgaris, Coleus, Commiphora myrrha
6
What herb(s) can potentiate (INC) anticoagulation therapy (I.e. Warfarin)?
What herb(s) can antagonize or block anticoagulation therapy (i.e. Warfarin)?
Allium cepa/sativum, Angelica sinensis, Capsella, Capsicum, Chamaelirium, Curcuma
Blocks - Ceanothus, Equisetum
7
What herbs can decrease drug absorption d/t polysaccharide action?
Aloe vera gel
Althea officinalis
Astragalus membranaceus
8
What herbs must avoid hypokalemic drugs?
And what are hypokalemic drugs?
Aloe vera latex, Cassia
Cathartics, Convallaria, Digitalis, Equisetum
Diuretics (Furosemide, HCTZ)
Corticosteroids (Hydrocortisone, Prednisone, Dexamethasone)
Cardiac glycosides (Digoxin, Convallaria, Digitalis, Leonarus)
Anti-Arrhythmias (atenolol, propranolol, amiodarone)
Pseudoephedrine
Glycyrrhiza
9
What herbs should be avoided if undergoing anti-PLT therapy d/t anti-PLT action?
Angelica sinensis
10
What herb is less effective when urine is acidified by Vit. C or cranberry?
Arctostaphylos uva ursi
11
What herb is more effective when combined with iron?
Artemisia annua
12
What herbs interact with cardiac glycosides (digoxin, convallaria, digitalis, leonarus)?
Asclepias tuberosa, Coleus, ***
13
What herbs can increase the action of Acyclovir and Interferon 1 and 2?
Astragalus membranaceus
14
What herbs can decrease the action of corticosteroids (hydrocortisone, prednisone, dexamethasone?
Astragalus membranaceus
15
What herbs can increase the action of anticholinergic drugs (i.e. atropine, bupropion, dextromethorphan, dicyclomine, diphenhydramine, tiotropium bromide, tolterodine, TCAs, amantadine)?
Atropa belladonna
Datura
16
What herb(s) induce CYP450?
Bacopa, Capsicum, Commiphora mukul,
17
What herb(s) INC thyroid hormone and potentiates (INC) Levothyroxine?
Bacopa
18
What herb(s) potentiate CCBs (i.e. Amlodipine)?
Bacopa
19
What herb(s) potentiate Sedative drugs?
What herb(s) antagonize sedative drugs?
What are some sedative drugs?
Bacopa (INC)
Camellia (DEC)
Antihistamines: Diphenhydramine, Hydroxyzine
Barbiturates: Phenobarbital
Benzos: Alprazolam/Diazepam
Opiates: Codeine, Hydrocodone, Morphine, Oxycodone, Methadone
Trazadone
Zolpidem
20
What herb(s) potentiate (INC) Barbiturates (Phenobarbitol)?
Bacopa
Berberis vulgaris
21
What herb(s) enhance NSAIDs (aspirin, ibuprofen, naproxen, celecoxib)?
Boswellia
Camellia
Coleus
22
What herb dec iron absorption?
Camellia
23
What herb(s) enhance the action of acetaminophen, clopidogrel, doxorubicin and warfarin?
Camellia
24
What herb(s) INC CNS stimulants?
What are CNS stimulants?
Camellia
(i.e caffeine, dextroamphetamine MDMA, methylphenidate, modafinil, pseudoephedrine)
25
Camellia when combined with what drug can lead to HTN?
MAOIs (Phenelzine)
26
What 3 drugs can effect caffeine with Camellia and in what way?
Ciprofloxacin (inhibits caffeine elimination)
Phenytoin (INC elimination of caffeine)
OCPs INC caffeine effects
27
What 2 drugs inhibit metabolism and INC/enhances action of Camellia?
Inhibit: Clozapine
Enhance: Amitriptyline
28
What herb(s) INC action of opiates and barbiturates?
Cannibis
29
Capsicum has a specific interaction with an Anti-HTN medicine, whats the med and interaction?
Enhances cough SE with ACEi (Lisinopril)
30
