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Flashcards in Herb-Drug Interactions Deck (45)
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1

What herb interacts with PPIs and why?

Achillea millefolium, Arctium lappa, Artemisia absinthium/vulgaris, Berberis aquifolium/vulgaris, Coleus, Cynara

D/t bitter properties and stimulation of HCl in the gut

2

What herbs can decrease drug absorption d/t increasing GI motility?

Achillea millefolium, Aloe vera latex, Arctium lappa, Artemisia absinthium/vulgaris, Berberis aquifolium/vulgaris, Cassia, Cynara

3

What herbs are contraindicated when combined with HRT can lead to estrogen excess?

Actaea racemosa (black cohosh), ***

4

What herb can decrease hot flashes caused by Tamoxifen?

Actaea racemosa

5

What herb(s) can cause hypoglycemic effects when combined with oral hypoglycemic meds (i.e. Metformin, Glyburide, Rosiglitazone, Insulin)?

Allium cepa/sativum, Aloe vera gel (internally), Arctium lappa, Artemisia vulgaris, Coleus, Commiphora myrrha

6

What herb(s) can potentiate (INC) anticoagulation therapy (I.e. Warfarin)?

What herb(s) can antagonize or block anticoagulation therapy (i.e. Warfarin)?

Allium cepa/sativum, Angelica sinensis, Capsella, Capsicum, Chamaelirium, Curcuma

Blocks - Ceanothus, Equisetum

7

What herbs can decrease drug absorption d/t polysaccharide action?

Aloe vera gel
Althea officinalis
Astragalus membranaceus

8

What herbs must avoid hypokalemic drugs?

And what are hypokalemic drugs?

Aloe vera latex, Cassia
Cathartics, Convallaria, Digitalis, Equisetum

Diuretics (Furosemide, HCTZ)
Corticosteroids (Hydrocortisone, Prednisone, Dexamethasone)
Cardiac glycosides (Digoxin, Convallaria, Digitalis, Leonarus)
Anti-Arrhythmias (atenolol, propranolol, amiodarone)
Pseudoephedrine
Glycyrrhiza

9

What herbs should be avoided if undergoing anti-PLT therapy d/t anti-PLT action?

Angelica sinensis

10

What herb is less effective when urine is acidified by Vit. C or cranberry?

Arctostaphylos uva ursi

11

What herb is more effective when combined with iron?

Artemisia annua

12

What herbs interact with cardiac glycosides (digoxin, convallaria, digitalis, leonarus)?

Asclepias tuberosa, Coleus, ***

13

What herbs can increase the action of Acyclovir and Interferon 1 and 2?

Astragalus membranaceus

14

What herbs can decrease the action of corticosteroids (hydrocortisone, prednisone, dexamethasone?

Astragalus membranaceus

15

What herbs can increase the action of anticholinergic drugs (i.e. atropine, bupropion, dextromethorphan, dicyclomine, diphenhydramine, tiotropium bromide, tolterodine, TCAs, amantadine)?

Atropa belladonna
Datura

16

What herb(s) induce CYP450?

Bacopa, Capsicum, Commiphora mukul,

17

What herb(s) INC thyroid hormone and potentiates (INC) Levothyroxine?

Bacopa

18

What herb(s) potentiate CCBs (i.e. Amlodipine)?

Bacopa

19

What herb(s) potentiate Sedative drugs?

What herb(s) antagonize sedative drugs?

What are some sedative drugs?

Bacopa (INC)

Camellia (DEC)

Antihistamines: Diphenhydramine, Hydroxyzine
Barbiturates: Phenobarbital
Benzos: Alprazolam/Diazepam
Opiates: Codeine, Hydrocodone, Morphine, Oxycodone, Methadone
Trazadone
Zolpidem

20

What herb(s) potentiate (INC) Barbiturates (Phenobarbitol)?

Bacopa
Berberis vulgaris

21

What herb(s) enhance NSAIDs (aspirin, ibuprofen, naproxen, celecoxib)?

Boswellia
Camellia
Coleus

22

What herb dec iron absorption?

Camellia

23

What herb(s) enhance the action of acetaminophen, clopidogrel, doxorubicin and warfarin?

Camellia

24

What herb(s) INC CNS stimulants?

What are CNS stimulants?

Camellia

(i.e caffeine, dextroamphetamine MDMA, methylphenidate, modafinil, pseudoephedrine)

25

Camellia when combined with what drug can lead to HTN?

MAOIs (Phenelzine)

26

What 3 drugs can effect caffeine with Camellia and in what way?

Ciprofloxacin (inhibits caffeine elimination)

Phenytoin (INC elimination of caffeine)

OCPs INC caffeine effects

27

What 2 drugs inhibit metabolism and INC/enhances action of Camellia?

Inhibit: Clozapine

Enhance: Amitriptyline

28

What herb(s) INC action of opiates and barbiturates?

Cannibis

29

Capsicum has a specific interaction with an Anti-HTN medicine, whats the med and interaction?

Enhances cough SE with ACEi (Lisinopril)

30

What herbs(s) can interfere with angina tx and why?

Caulophyllum d/t vasoconstrictive action to heart vessels