dermatology Flashcards

1
Q

common location SCC

A

lower lip, head and neck, external ear, forehead, scalp

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2
Q

in melanoma, when does vertical growth phase occur

A

after radial growth

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3
Q

Basal cell typically located

A

upper lip (rarely mets)

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4
Q

drugs that can cause psoriasis

A

beta blockers, lithium, NSAIDs, ethanol

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5
Q

Bullous pemphigoid pathophysiology

A

IgG Abs against dermal-epidermal basement membrane proteins (hemidesmosomes) -> leads to supepidermal bullae

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6
Q

Bullous pemphigoid and Pempigus vulgaris imaging

A
  • immunofluorescence shows linear deposits of IgG and C3
  • in base memb in BP (deep)
  • in epidermis in PV (superficial)
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7
Q

Bullous pemphigoid negative or positive Nikolsky’s sign?

A

negative

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8
Q

Pempigus vulgaris typical age and culture

A

40-60 (and higher prevalence in jewish, mediterranean, asian people)

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9
Q

bullous pemphigoid typical age

A

60-80

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10
Q

Pempigus vulgaris Nikolsky’s sign

A

sliding or rubbing pressure on skin causes suparation of epidermis

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11
Q

most common causes of erythema multiforme

A

mycoplasma pneumonia, HSV (rarely drugs - sulfonamides, penicillin, phenytoin)

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12
Q

pityriasis rosea is typically from

A

Human Herpesvirus 7

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13
Q

pityriasis rosea begins as a what, which develops into a what?

A

herald patch –> christmas tree distribution on trunk

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14
Q

a furuncle is aka

A

boil

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15
Q

what is a furuncle

A

deep folliculitis (infx of hair follicle) usually from staph a

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16
Q

what is a felon

A

subcutaneous abscess on fingertip - usually occurs after severe paronychia or puncture wound on finger pad

17
Q

what is a carbuncle

A

abscess larger than a boil, deep seated from multiple furuncles

18
Q

vitiligo can be caused by what autoimmune conditions

A

hashimotos, hypoparathyroidism, addison’s, Type 1 DM

19
Q

Tx for impetigo

A

mupirocin (protein synth inhib)