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Flashcards in MSK Pharm Deck (13)
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1

Selective Estrogen Receptor Modulator (SERM)

Raloxifene

2

Raloxifene

Estrogen modulator and Bone health

SE: Most common: hot flashes
endometrial cancer
increased risk of DVT (like birth control)

3

Bisphosphonate for osteoperosis

ALENDRONATE

take an upright position 30 mins before food with full glass of plain water
SE: esophageal erosion/ c/i in esophageal pathology
black tarry stools and coffee ground vomit

4

nutrients depleted with opioids

folic acid
vitamin C
iron
potassium

5

allopurinol

preventing further GOUT attacks
prevention of uric acid nephropathy during cancer chemo

SE: GI upset and maculopapular rash

6

colchicine

acute or first time GOUT

7

which steroids are oral

prednisone

prednisolone

methylprednisolone

dexamethasone

hydrocortisone

8

which steroids are oral

prednisone

prednisolone

methylprednisolone

dexamethasone

hydrocortisone

9

which steroids are inhaled

fluco

10

Celecoxib

cox 2 selective inhibitor

in osteoarthritis, rheumatoid arthritis (RA), and ankylosing spondylitis; management of acute pain in adults; treatment of primary dysmenorrhea; relief of signs and symptoms of juvenile RA

11

Celecoxib

cox 2 selective inhibitor

in osteoarthritis, rheumatoid arthritis (RA), and ankylosing spondylitis; management of acute pain in adults; treatment of primary dysmenorrhea; relief of signs and symptoms of juvenile RA

if taken with FLUCANAZOLE: increases concentration of the drug

12

muscle relaxant

Cyclobenzaprine, Flexeril

Carisoprodol, Soma (controlled substance)
-

Methocarbamol, Robaxin: may turn urine black, blue, or green

13

Muscle Spasticity

Botulinum toxin, Botox
upper/lower limb spasticity

Baclofen, Lioresal : for MS *not parkinsons*
MoA unknown
Uses: spasticity of MS, spinal cord injury, rheumatic disorders. NOT indicated for stroke, cerebral palsy, and Parkinson’s disease has not been established and, therefore, it is not recommended for these conditions
TAPER off if discontinuing (hallucinations/seizures)
SE: drowsiness, asthenia, dizziness, headache, nausea

Tizanidine, Zanaflex: Alpha-2-adrenergic agonist