Neuro Flashcards

1
Q

Glioblastoma pathology

A

GFAP stained astrocytes

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2
Q

Neurofibromatosis gene

A

NF1 chromosome 17(neurofibromin tumor suppressor protein in myelin)

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3
Q

von-hippel lindau gene

A

VHL chromosome 3(autoD, tumor suppressor)

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4
Q

MS pathology

A

oligoclonal bands& periventricular plaques

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5
Q

Guillan-Barre causes

A

campylobacter jejuni, CMV& vaccines

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6
Q

Acute disseminated encephalomyelitis causes

A

measles, VZV& vaccines

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7
Q

Krabbe’s deficiency

A

galactocerebrisidase

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8
Q

metachromic leukodystrophy deficiency

A

arylsulfatase A

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9
Q

Alzheimers genes

A

presenilin, APP& ApoE4.

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10
Q

Alzheimers pathology

A

B-amyloid, tau protein& neurofibrillary tangles

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11
Q

Horner’s syndrome causes

A

pancoast tumor& brown sequard(above T1)

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12
Q

Friederich’s ataxia deficiency

A

frataxin

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13
Q

lateral hypothalamus

A

hunger center

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14
Q

ventromedial hypothalamus

A

satiety center

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15
Q

anterior hypothalamus

A

cooling&PS center

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16
Q

posterior hypothalamus

A

heating&sympathetic center

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17
Q

VPL

A

body sensation

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18
Q

VPM

A

face sensation

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19
Q

LGN

A

vision

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20
Q

MGN

A

hearing

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21
Q

VL

A

motor

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22
Q

parkinsons deposits

A

lewy bodies(a-synuclein)

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23
Q

parkinsons brain loss

A

substantia nigra pars compacta(dopaminergic)

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24
Q

Huntingtons genes

A

CAG repeats

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25
Q

huntingtons brain loss

A

caudate(GABAergic neurons)

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26
Q

kluver bucy lesion

A

amygdala

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27
Q

wernicke-korsakoff lesion

A

mammilary bodies(thiamine deficiency)

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28
Q

locked-in lesion

A

central pontine myelinosis

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29
Q

Berry anyeurism location

A

cicle of willis bifurcations

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30
Q

epidural hematoma

A

middle meningeal A(not X sutures)

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31
Q

subdural hematoma

A

bridging veins(crescent+X sutures)

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32
Q

subarachoid hemorrhage

A

berry anyeurism rupture

33
Q

poliomyelitis lesion

A

anterior horn

34
Q

werdnig-hoffman lesion

A

anterior horn

35
Q

ALS common defect

A

superoxide dismutase 1

36
Q

ALS lesion

A

UMN+LMN(no sensory, cognitive or oculomotor)

37
Q

syringomyelia associated defect

A

chiari 1 malformation

38
Q

B12/vitamin E deficiency lesion

A

dorsal columns+lateral CST+spinocerebellar

39
Q

acoustic schwannoma association

A

neurofibromatosis type 2

40
Q

schwannoma associated cell marker

A

s100

41
Q

most common brain tumor

A

glioblastoma

42
Q

hemangioblastoma association

A

von-hippel lindau disease

43
Q

most common childhood brain tumor

A

craniopharyngioma

44
Q

short procedure anesthetics

A

barbiturates(thiopental)& propofol

45
Q

malignant hyperthermia treatment

A

dantrolene

46
Q

Sign of neural tube defects

A

elevated AFP

47
Q

sign of anencephaly

A

polyhydraminos

48
Q

typical syringomyelia levels

A

C8-T1

49
Q

friedrich’s ataxia association

A

hypertrophic cardiomyopathy

50
Q

neonatal meningitis bugs

A

group B strep, listeria &Ecoli

51
Q

infant meningitis

A

H influenza

52
Q

adolescent/adult meningitis

A

neisseria M

53
Q

most common viral meningitis

A

cocksackie

54
Q

moderate brain ischemia lesions

A

cortical laminar necrosis, pyramidal neurons& cerebellar purkinje neurons

55
Q

thrombotic stroke color

A

pale

56
Q

embolic stroke characteristic

A

hemorrhagic

57
Q

lacunar stroke vessels

A

lenticulostriate

58
Q

ischemic stroke lesion

A

red neurons(liquefactive)

59
Q

berry anyeurism associations

A

Marfan&ADPKD

60
Q

multifocal leukoencephalopathy cause

A

JC virus

61
Q

decreased risk of alzheimers gene

A

ApoE2

62
Q

populations at risk for alzheimers

A

elderly&downs syndrome

63
Q

Picks disease areas affected

A

frontal& temporal lobes

64
Q

spongiform protein dysfunction

A

beta sheet prions

65
Q

Guillian-Barre Tx

A

IVIG, plasmaphoresis, respiratory support

66
Q

MS Tx

A

IFN-beta

67
Q

Wilson’s Disease pathology

A

kaiser-fleischer rings

68
Q

Gq phospholiase C receptors

A

M3, CCK-B

69
Q

Gi adenyl cyclase receptors

A

somatostatin, PG

70
Q

Gs adenyl cylase receptors

A

H2

71
Q

stage I sleep waves

A

theta

72
Q

stage 2 sleep waves

A

sleep spindles, k complex

73
Q

stage 3 sleep waves

A

delta

74
Q

REM sleep waves

A

beta

75
Q

NF gene type

A

tumor suppresor

76
Q

brain tumor with rounded cells+fine branching capillaries, frontal lobe

A

oligodendroglioma

77
Q

right hemiparesis&proprioceptive loss, tongue deviates left

A

left medial medullary(ASA paramedian branches)

78
Q

dysphagia, hoarseness, right horners, ataxia, decreased pain&temp

A

lateral medullary-wallenberg(PICA)

79
Q

facial paralysis, nystagmus, right pain&temp/hearing loss&right horners

A

lateral pontine(AICA)