Renal Flashcards

(56 cards)

1
Q

Most common site of fetal obstruction

A

ureteropelvic junction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

potters syndrome cause (limb/facial/pulmonary hypoplasia)

A

oligohydramnios

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

horseshoe kidney association

A

turner syndrome(under IMA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

clearance equation

A

UV/P

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

RBF equation

A

RPF/(1-Hct)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

angiotensin II sites of action

A

efferent arteriole, ADH, NA-H exchange PCT(contraction alkalosis), AT1 vascular SM, aldosterone, hypothalamus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

glucose clearance threshold

A

140

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

RAAS system sensors

A

JG cells=BP, macula densa=Na delivery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

ANP mechanism

A

sense atrial pressure, relaxes SM via cGMP, Na loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

NSAIDs renal failure mechanism

A

inhibit prostaglandins that dilate afferent arteriole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

anion gap

A

Na-(Cl+HCO3)>12, MUDPILES(normal=HARDASS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

fatty casts in urine

A

nephrotic syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

brown casts

A

tubular necrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

waxy casts

A

chronic/advanced renal disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

nephrotic

A

proteinuria(>3.5), edema, fatty casts, hyperlipidemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

acetazolamide (CA inhibitor) use

A

altitude sickness/alkalosis/glaucoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

loop(furosemide/ethacrynic acid) toxicity

A

oto, low K, gout

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

thiazide MOA

A

Block DCT NaCl symporter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

thiazide toxicity

A

hyperlipid/Ca/uric/glucose, low Na

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Angiotensin II SE+mediator

A

dry cough& angioedema-bradykinin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

polycystic kidney disease associations

A

hepatic fibrosis(autoRecessive), berry anyeurism(autoD)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Acute renal failure hallmark

A

azotemia, oliguria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

BUN:Cr>15

A

pre& early post renal

24
Q

BUN:Cr<15

A

tubular damage(late postrenal)

25
common renal tubular damage drugs
aminoglycosides, heavy metal, myoglobin, ethylene glycol
26
minimal change disease association
Hodgkins Lymphoma(cytokines)
27
minimal change disease pathology
effaced foot processes, selective proteinuria(not IG)
28
Focal segmental glomerulonephritis associations
HIV, heroin, sickle cell(nonresponsive to steroids MCD)
29
membranous associations
SLE, hepB&C, tumors, drugs
30
membranous pathology
subepithelial IC deposition-granular/spike and dome
31
membranoproliferative pathology
tram track(type I-subendothelial-hepB&C, II-basement membrane-C3 nephritic factor)
32
DM kidney pathology
NEglycosylation of basement membrane, hyaline arteriolosclerosis, kimmelstein wilson nodules
33
nephritic syndrome mediator
C5a neurophils
34
PostStrep GN pathology
hypercellular, IC lumpy bumpy
35
rapidly progressive pathology
fibrin+M0 crescents in bowmans space
36
specific rapidly progessive disease pathology
goodpasture-linear(+hemoptysis), pauci immune(no deposits), PSGN/diffuse proliferative(granular)
37
most common SLE renal association
diffuse proliferative GN(also membranous less likely)
38
pauci immune pathology
wegeners-cANCA+lung+nasopharynx, churg-strauss-pANCA/eosinophils/asthma/granulomas, microscopic polyangiitis-pANCA
39
Bergers pathology
mesangium IgA deposits, following mucosal infections
40
alport genes
X-linked type IV collagen, split basement membrane+deaf
41
UTI labs
WBCs, leukocyte esterase, nitrites
42
Vesicoureteral reflux findings
scarring inferior&superior poles
43
chronic pyelonephritis findings
waxy casts, proteinaceous follicles from atrophic tubules
44
most common stone
CaP/oxalate(crohns/hypercalcemia association)
45
AMP(struvite) pathology
urease+(proteus/klebsiella), staghorn, alkaline urine
46
uric acid stone pathology
radiolucent, gout, acidic(Tx alkalinize)
47
cysteine stone association
children, staghorn
48
EPO creation
renal peritubular interstitial cells
49
dialysis association
renal cell carcinoma
50
angiomyolipoma association
tuberous sclerosis
51
renal cell carcinoma paraneoplastic syndromes
EPO, renin, PTHrP, ACTH excess
52
renal cell genetics
loss VHF tumor suppressor(higher IGF, VEGF, PDGF) von hippel lindau association, chromosome 3
53
most common tumor in kids+pathology
wilms-blastema cells(WT1 mutation)
54
most common lower UT tumor
urothelial carcinoma(bladder) SMOKING, flat or papillary
55
squamous cell lower UT associations
Schistosoma hematobium(Middle eastern male), chronic cystitis, long standing stone
56
adenocarcinoma association
urachal remnant(dome of bladder), exstrophy, cystitis