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Flashcards in Osteoporosis Deck (5)
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1

What are the possible iatrogenic causes of osteoporosis?

Steroids
Anti-epileptics
Anticoagulants
PPI's
TZD's
Lithium

2

What type of drug is Alendronate?

Nitrogenous Bisphosphonate

3

What are the 3 serious adverse effects of Alendronate?

Angioedema
Uveitis
Scleritis

4

What is the MOA of Alendronate?

Affinity for Co2, it accumulates in bone, is ingested by osteoclasts, it kills them by inhibiting HMG-CoA reductase, and reduces bone resporption

5

What are the indications for Alendronate?

Osteoporosis
Paget's Bone disease