Anti-Rheumatics Flashcards Preview

Systemic Pharm > Anti-Rheumatics > Flashcards

Flashcards in Anti-Rheumatics Deck (12)
Loading flashcards...
1

What may happen when HCQ and Botox interact?

Impaired Botox activity

2

What are the 3 indications for HCQ?

Rheumatoid Arthritis Systemic Lupus Erythematosus Malaria prophylaxis

3

Name 3 DMARDs

Hydroxycholorquine (HCQ) Chloroquine Methotrexate

4

HCQ can inhibit activity of which drug?

Botox

5

What is the potential hypersensitivity to HCQ?

Angioedema

6

What is the MOA of HCQ?

Inhibits rheumatoid factor and acute phase reactants

Interrupts parasitic vesicle functions and phospholipid metabolism by increasing pH

7

What is the contraindication of HCQ?

Retinal or visual changes

8

What are the serious ocular adverse effects of HCQ?

Retinopathy

Vision changes

9

Which is more toxic, HCQ or Chloroquine?

Chlolorquine

10

What are the 2 common adverse effects of HCQ?

Headache

Photosensitivity

11

HCQ dosing of over ___g per day places the eyes at great risk for retinal toxicity.

1000g

12

What effects can HCQ have on the cornea?

Verticillata

Vortex keratopathy