Pathoma: Colorectal Carcinoma (2)

Question 1

The most common pathway for colorectal carcinoma is ______________. The second-most common is ____________.

Answer 1

adenoma-carcinoma sequence; microsatellite instability

Question 2

Microsatellites occur in ___________ DNA.

Answer 2

noncoding

Question 3

Other than HNPCC, mutations in mismatch-repair enzymes increase risk for ______________.

Answer 3

ovarian and endometrial cancer

Question 4

True or false: HNPCC recapitulates glandular tissue.

Answer 4

False. It is a carcinoma.

Question 5

Colorectal cancer screening begins at age _____.

Answer 5

50

Question 6

Napkin-ring lesions in the left colon do what to stool?

Answer 6

Decreases the caliber of the stool (leading to “pencil-thin” poops)

Question 7

__________ usually arises in the right colon, while ____________ usually arises in the left.

Answer 7

Carcinoma; adenocarcinoma

Question 8

Those with colorectal carcinoma are at increased risk of infection with what bacterium?

Answer 8

Streptococcus bovis endocarditis

Question 9

CEA is useful not as a screening measure, but to evaluate ____________.

Answer 9

treatment response