Pathoma: Small Bowel Flashcards

1
Q

Duodenal atresia is common in __________.

A

those with Down syndrome

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2
Q

How can you differentiate pyloric stenosis from duodenal atresia?

A

Duodenal atresia presents with bilious vomiting!

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3
Q

What is the double-bubble sign?

A

In duodenal atresia, the duodenal stub dilates and the stomach dilates, but the pylorus remains tight, leading to a double bubble on x-ray.

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4
Q

Embryos receive their nutrients from the ___________.

A

vitelline duct (“it is VITaL to have the VITeLline duct”)

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5
Q

What are the rules of 2 for Meckel diverticulum?

A

It is present in 2% of the population (most common GI malformation); it is two inches long; and it is found on the SMALL INTESTINES within two feet of the ileocecal valve.

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6
Q

What are the two most common locations for volvulus by age?

A

Young people: cecum

Elderly: sigmoid colon

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7
Q

Intussusception most often occurs in what direction?

A

The proximal edge gets dragged into the distal edge; in children, lymphoid hyperplasia acts as a catalyst, and in adults tumors do.

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8
Q

Marked hypotension leads to _______ ischemic damage, while ___________ leads to transmural damage.

A

mucosal; thrombosis

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9
Q

Lactose intolerance can be triggered by ___________.

A

GI infection

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10
Q

Celiac is associated with ________ (MHC).

A

HLA-DQ2 and HLA-DQ8

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11
Q

What causes damage in celiac?

A

The deamidated gliadin is grabbed by APCs and shown to helper Ts which generate inflammation.

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12
Q

IgA deposits in the _________ to cause dermatitis herpetiformis.

A

dermal papillae

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13
Q

What is endomysium?

A

Lining around muscle fibers

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14
Q

Which part of the small intestine is most affected in celiac?

A

Duodenum

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15
Q

What infectious disorder mimics celiac?

A

Tropical sprue (due to an unknown organism)

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16
Q

Other than patient history, how can you differentiate tropical sprue and celiac?

A

Celiac affects duodenum

TS affects jejunum and ileum

17
Q

Chylomicrons are packaged in ___________.

A

enterocytes

18
Q

Enlarged macrophages that clog lacteals presents in ___________.

A

Whipple’s

19
Q

Look up abetalipoproteinemia.

A

Got it.

20
Q

The most common site of carcinoid tumors is the _________.

A

small bowel

21
Q

Carcinoid syndrome arises when the tumor ____________.

A

metastasizes to the liver

22
Q

What is carcinoid heart disease?

A

Right-sided valvular fibrosis from serotonin (leading to tricuspid regurgitation and pulmonary valve stenosis)

23
Q

Why doesn’t carcinoid syndrome affect the left heart?

A

Because the lung also has MAO and degrades the serotonin