perinatal infections-HSV

Question 1

Herpes simplex virus pathogen and way of transmission

Answer 1

is a DNA herpes virus that is
spread by intimate mucocutaneous contact. ( skin cut)

Most genital herpes results from HSV II, but can also
occur with HSV I.

Transplacental transmission from mother to fetus can
occur with viremia during the primary infection or
recurrent infection

The most common route of fetal infection is contact
with maternal genital lesions during delivery.

Question 2

The most common route of fetal infection is

Answer 2

contact
with maternal genital lesions during delivery.

Question 3

Most genital herpes results from

Answer 3

HSV II, but can also
occur with HSV I.

Question 4

fetal infection complications

Answer 4

*spontaneous abortions
*symmetric IUGR,
microcephaly,
and cerebral calcifications.

Question 5

Neonatal infection complications

Answer 5

*meningoencephalitis
*Pneumonia
*hepatosplenomegaly, jaundice, and petechiae.

Question 6

Prevention of transmission if the mother had previous HSV infection

Answer 6

**antiviral suppression start at 36 weeks (acyclovir )

** vaginal delivery if no lesions /prodromal symptoms during labor ..if there is = c-section

Question 7

Prevention of transmission if the mother didn’t had previous HSV infection(no prior HSV lesions in genitalia region)

Answer 7

routine prenatal care