perinatal infections- parvovirus

Question 1

Parvovirus B19 pathogenicity

Answer 1

is a DNA virus also known as fifth disease. It is a common childhood illness
. cytotoxic to fetal RBC precursors
* Vertical transmission is transplacental at the time of primary viremia.

Question 2

Parvovirus B-19 characteristics

Answer 2

*cytotoxic to fetal RBC precursors and may cause fetal
anemia and hydrops fetalis
*Fetal infection cause nonimmune hydrops is seen more
commonly with infections prior to 32 weeks.
*characterized by a “slapped cheek” appearance on the face.

Question 3

Parvovirus B-19 prevention

Answer 3

. Pregnant women exposed to parvovirus
should have serologic testing for IgG and IgM antibodies.