perinatal infections-Toxoplasmosis

Question 1

Toxoplasmosis pathogenesis

Answer 1

Toxoplasmosis is caused by a parasite (Toxoplasma gondii) transmitted most
from exposure to infected cat feces. gout milk, infected raw meat
* Up to 40% of pregnant women are toxoplasmosis IgG seropositive

Question 2

Fetal infection: Manifestations may include

Answer 2

*symmetric IUGR
*nonimmune fetal hydrops(mostly seen in parvo virus )
*Microcephaly
*intracranial calcifications.

Question 3

Treatment:

Answer 3

spiramycin to prevent vertical transmission (from the mother to the fetus)

Question 4

congenital toxoplasmosis (4c’s)

Answer 4

*cerebral calcifications
*cephaly(micro)
*cephalus(hydro
*chorioretinitis
*convulsions