perinatal infections-rubella

Question 1

rubella pathogenesis

Answer 1

*transmitted via respiratory droplets
*transplacental to fetus
*a highly contagious RNA virus that is spread by respiratory droplets.
* Up to 85% of pregnant women are rubella IgG seropositive.
* Vertical transmission from mother to fetus occur during the viremia of a primary
infection because the result is residual lifelong immunity.

Question 2

Congenital rubella syndrome is characterized by

Answer 2

1. congenital deafness (most common sequelae)
2. congenital heart disease (PDA)
3. Cataracts
4. intellectual disability
5. hepatosplenomegaly, thrombocytopenia, skin rash

Question 3

Treatment.

Answer 3

No specific treatment is available

Question 4

classical triad of congenital rubella

Answer 4

1)cardiac abnormalities
2)cataract
3)deafness