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Flashcards in Resp 10 - Lung cancer Deck (19):
1

What is the 5 year survival rate of Lung cancer?

~ 15%

2

List some causes of lung cancer:

- Smoking
- Asbestos
- Radon exposure
- Occupational carcinogens ie Chromium/Nickel/Arsenic
- Genetic factors

3

What are some signs/symptoms of a primary lung cancer?

MOST COMMONLY ASYMPTOMATIC
- Cough
- Dyspnoea
- Wheezing
- Haemoptysis
- Lung infection
- Chest/Shoulder pain
- Weight loss
- Lethargy/malaise

4

Why may patients with lung cancer have a bloated face?

Obstruction of superior vena cava = local oedema

5

Why may patients with lung cancer develop a hoarse voice?

Tumour may damage the left recurrent laryngeal nerve, which innervates left vocal cord

6

What is the most common cause of finger clubbing?

Hypoxaemia

7

What conclusion can you make about someones lung cancer if they have pale conjunctiva?

Cancer has metastasised to bone
= decreased blood cell production

8

Describe horners' syndrome:

- Miosis
- Partial ptosis
- Hemifacial loss of sweating

Due to interrupted sympathetic nerve supply to eye

9

What are the differential diagnoses of a dense consolidation 'lump' seen on a chest xray?

- Fat
- Infection
- Scar
- Cyst
- Tumour

10

What system is use to stage lung cancer?

TNM staging system

11

Which 2 types of lung cancers are usually caused by smoking?

1) Small cell carcinoma
2) Squamous cell carcinoma

12

Which lung cancer is often associated with ectopic ADH and ACTH secretion?

Small cell carcinoma

13

Which 2 syndromes may be caused by ectopic hormone secretions from a small cell lung cancer? What are the hormones?

1) SIADH due to ectopic ADH
2) Cushing's syndrome due to ectopic ACTH

14

Which lung cancer is associated with PTHrP secretion?
What does this cause?

Squamous cell carcinoma
Hypercalcaemia

15

What is the most common type of lung cancer in non-smokers?

Adenocarcinoma

16

Which type of lung cancer has the best prognosis (slow-growing)?

Adenocarcinoma

17

What type of lung cancer is undifferentiated and lacks the diagnostic features of the other lung cancers?

Large cell carcinoma

18

Where do lung cancers typically metastasise to?

- Brain
- Bones
- Liver
- Adrenal glands

19

Which type of lung cancer is most likely to be operable?

Small cell lung cancer