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Flashcards in Stem Cells Deck (11):

Embryonic Stem Cells

Pluripotent/Undifferentiated cells. -Not Specialized
-Made from the union of egg and sperm cell
-Very generic cell. Doesn't do anything but divide. It makes more copies of itself.
-As they continue to divide they start to undergo differentiation.-Becoming more specialized.


What are Embryonic Stem Cells made from?

Union of egg and sperm cell


What 4 general tissue categories do Embryonic Stem Cells become?



Fully Differentiated Stem Cells

They have matured and become what they need to be.
-when they finally become a nervous, muscle, epithelial, or connective tissue.


Terminally Differentiated

No longer able to divide and make more of themselves.
-Nervous and some muscle tissues are this way.


3 Unique characteristics of Embryonic Stem Cells

- Capable of dividing and renewing for long periods
-Can give rise to specialized cell types


What are potential uses of stem cells?

-Cancer Research
-Birth Defects
-Testing new Drugs
-Cell Based Therapies
-Parkinsons, Alzheimer, spinal cord injuries, heart disease, burns, Diabetes(type 1)...


Where do embryonic Stem Cells come from?

-Derived from embryos
-Fertilized invitro
-4-5 days old
-about 30 cells
-They are leftover from fertility clinics that have been donated to research.
-Can be found in the umbilical cord
-Grown in cell cultures


Adult Stem Cells

-Undifferentiated cell found among differentiated cells.
-Can differentiate to major cell types of that tissue where they found it.


Advantages of Stem Cells

-Embryonic Stem cells truly pluripotent
-Embryonic Stem Cells are easy to grow/plentiful
-Cultured Adult Stem Cells are readily accepted back into the donor.


Disadvateges of Stem Cells

-Adult Stem Cells are rare in tissue and are not easily cultured.
-Immune system rejection of cultured embryonic stem cells