Strep Agalactiae, Enterococcus genus Flashcards
(15 cards)
1
Q
Strep Agalactiae General
A
- Colonizes Vagina, can also be found in male genital tract or colon
- Asymptomatic carrier women 10-30%
- Can reach 20-40% in pregnancy
2
Q
Strep Agalactiae Morphology
A
- Gram Positive
- Cocci (long chains)
- Encapsulated (polysaccharide)
- Lancefield B (GBS)
3
Q
Strep Agalactiae Cultivation
A
- Fastidious
- Blood agar + 5% CO2
- Whitish-greyish colonies
- B-hemolytic
4
Q
Strep Agalactiae Virulence factors
A
- Polysaccharide Capsule
- Pili
- C5a peptidase
- B-hemolysin
- Hyaluronidase
5
Q
Strep Agalactiae Neonatal Diseases
A
- Early onset: Pneumonia, Sepsis, less frequent meningitis (from birth canal)
- Late onset: Meningitis (#1 causative agent)
6
Q
Strep Agalactiae Adult Diseases
A
- Pregnant women: UTIs, Aminionitis, Endometritis, Postpartum Sepsis
- Elderly: Skin/Bone infections, Bacteremia, Urosepsis, Pneumonia
7
Q
Strep Agalactiae Treatment
A
- Penicillin!
- Ampicillin can also be used
- Intrapartum Prophylaxis (35w swab)
8
Q
Strep Agalactiae Microbiological Diagosis
A
- Bacitracin resistant
- CAMP positive (only one)
9
Q
Enterococci Species
A
- E. Faecalis (80-90%)
- E. Faecium (5-15%)
10
Q
Enterococci General
A
Normal Intestinal flora mostly large intestine
11
Q
Enterococci Morphology
A
- Gram Positive
- Cocci (pairs or short chains)
- Non-encapsulated
- Som motile
12
Q
Enterococci Cultivation
A
- Non fastidious
- Simple agar
- Greyish small colonies
- Non-hemolytic
- Lancefield D
- Bile-esculin media turn Black
13
Q
Enterococci Virulence factors
A
Biofilm making them nosocomial pathogens
14
Q
Enterococci Diseases
A
- UTI (catheters)
- Endocarditis, sepsis
- Biliary tree infections
- Intraabdominal infections (peritonitis)
15
Q
Enterococci Treatment
A
- MDR mostly E. Faecium
- Amoxicillin/Vancomycin + Gentamycin
- VRE: Linezolid, Tigecycline, Quinopristin-Dalfopristin
