Yersinia

Question 1

Yersinia Genus

Answer 1

• Gram Negative
• Rods
• Facultative Anaerobic
• Oxidase Negative
  (Y. Pestis & Enterocolitica)
• Zoonotic

Question 2

Y. Pestis General info

Answer 2

• Zoonotic
• Reservoir in rodents, rabbits
• Transmitted by rat Flea bite, so Flea vector
• Human to Human possible by respiratory droplets in late stages

Question 3

Y. Pestis Morphology

Answer 3

• Gram Negative Rod
• Facultative Anaerobic
• Easy to Culture

Question 5

Y. Pestis Diseases

Answer 5

Plague = Black death
- Bubonic plague: Painful buboes (lymph nodes), fever, 75% mortality if untreated, bacteremia
- Pneumonic plague: respiratory droplet spread, shorter incubation, fever, malaise, hemorr pneum, shock DIC, necrosis

Question 6

Y. Pestis Treatment

Answer 6

• Gentamycin
• Fluoroquinolones
• No vaccine

Question 7

Y. Pestis Microbiological Diagnosis

Answer 7

• Microscopy safety pin-like bipolar staining
• Only cultured in BSL-3 labs
• Fluorescent Antibody test for Fraction 1 antigen (f1)

Question 8

Y. Enterocolitica General Info

Answer 8

• Zoonotic, especially Pigs
• Tolerates cold temp

Question 9

Y. Enterocolitica Morphology

Answer 9

• Gram Negative Rods
• Facultative Anaerobic
• Easy to culture

Question 10

Y. Enterocolitica Diseases

Answer 10

• Gastroenteritis
• Pseudoappendicitis: seems like appendicitis but is pain due to abdominal lymph node inflammation

Question 11

Y. Enterocolitica Treatment

Answer 11

• Rehydration
• Fluoroquinolones if severe