Flashcards in T3-Analgesics: Headaches-MJ Deck (44)
What is the most common headache?
What headache is the disabling headache and needs aggressive treatment?
Migraines cause _____ head pain
What percent of migraines are unilateral?
What percent of migraines are bilateral?
Do migraines cause N/V?
Migraines cause a person to be sensitive to ___ and ___
Light and sound
What is the average length of a migraine?
So why do people get migraines when that is in the brain and the brain doesn't have pain receptors (you can poke, cut through the brain and no pain)?
Vessels and arteries IN THE BRAIN DO have pain receptors
Do migranes cause vasoconstriction or vasodialiaton?
Do migraines cause inflammation?
What nerve is effected from migraines?
What promotes migraines?
What surpasses migraines?
If we activate ______ receptors, that will depress the migraines.
Serotonin 1B,1D receptors
Which migraine medication stops a migraine AFTER it has started?
What are the 2 migraine specific drugs?
Serotonin 1B,1D agonists (triptans)
What are triptans selective to?
What nerve does triptans work on?
Trigeminal nerve complex
The triptans induce _______.
What do triptans block?
What are 3 examples of triptans?
What are the side effects of triptans (3)?
Vasoconstriction of coronary arteries
Heavy arms and chest pressure
We want triptans to induce _____ vasoconstriction, but the side effects sometimes cause vasoconstriction of ______.
We want them to induce CEREBRAL vasoconstriction but a side effect of triptans is causing vasoconstriction of CORONARY ARTERIES
Should you take a triptan if you have coronary artery disease or have had a MI? Why or why not?
NO! Side effect of triptan is vasoconstriction of coronary arteries !--NOT GOOD
Is the triptan side effect of heavy arms and chest pressure something to be concerned with?
No, UNLESS there are risk factors for the patient having heart problems
Triptans can also cause serotonin syndrome. Is this common or rare?
RARE unless taking some other drug that increases serotonin levels
What are the 4 big symptoms of serotonin syndrome?
Altered mental status
What are three drug classes that would cause too much serotonin when taking with a triptan?