T3-Asthma and COPD-MJ Flashcards Preview

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Flashcards in T3-Asthma and COPD-MJ Deck (44):
1

What are controllers?

Taken daily
NOT for acute symptoms

2

What are rescue meds?

Taken PRN
QUICK onset

3

What are the 5 major classes for asthma and COPD drugs?

1. SABAs
2. LABAs
3. Inhaled glucocorticoids
4. Short-acting anticholinergics
5. Long-acting anticholinergics

4

What does SABA stand for?

Short-acting beta agonists

5

What is the MOA of SABAs?

Lungs have beta2 receptors and whenever they are activated (by a SABA) they cause bronchodilation

6

SABAs:
Short or long acting?

Short

7

SABAs:
Slow or quick onset?

Quick onset

8

SABAs:
Short or long duration?

Short

9

SABAs: Controllers or rescue meds?

Rescue med

10

SABAs are reduce meds for ___ & ____.

COPD and asthma

11

What are adverse effects of SABAs?

They act on beta receptors, so the heart may be stimulated as well which would cause tachycardia, jitteriness, and headache

12

What are 2 examples of SABAs?

Albuterol
Levalbuterol

13

SABA: Levalbuterol was made with the thought of reducing the adverse effects of tachycardia (since albuterol has that effect). It was found that the levalbuterol can reduce the tachycardia by 4bmp. Is this good?

No, that is basically not helpful at all with that side-effect.

Levalbuterol had good intentions but it does not help reduce any tachycardia. Levalbuterol is basically a more expensive version of albuterol. It is the same drug essentially.

14

What does LABA stand for?

Long-acting beta agonists

15

What is the MOA of LABA?

Activate beta receptors in the lungs causing bronchodilation

16

LABA: Slow or fast onset?

Slow

17

LABA: Short or long duration?

Long

18

How long does it take a LABA to work?

2-3 hours

19

What is LABA good for?

COPD

20

What does LABA have a black box warning for?

ASTHMA-->it is CONTRAINDICATED to take a LABA if you have asthma!!! You can not take a LABA by itself if you have asthma. You ave to take it in addition to an actual asthma med!!!

*asthma related deaths is what caused this BBW

*African americans seemed to have this more

21

What are the adverse effects of LABA?

Same as SABAs (tachycardia, jitteriness, and headache)

22

What are the two types of LABA?

Formoterol
Salmeterol

23

Inhaled glucocorticoids are great for _____.

Asthma

24

Are inhaled glucocorticoids controllers or rescuers?

Controllers

25

How long does it take for an inhaled glucocorticoid to work?

What are the adverse effects of inhaled glucocorticoids?

1-2 weeks

Thrush--teach the patient to rinse out mouth after spraying

26

What receptors do glucocorticoids work on?

What are the two glucocorticoid drugs?

None- TRICK QUESTION
They are anti-inflammatory drugs

Fluticasone
Budesonide

27

Short-acting anticholinergics: Short or fast acting?

Short acting

28

Are short-acting anticholinergics controllers or rescue meds?

Rescue

29

Short-acting anticholinergics are best for _____.

COPD

30

If you are taking a short-acting anticholinergics, how long does it take to work?
(like exact timing answer)

It will start working in 30 seconds and by 3 min, it has reached 50% max effectivness

31

Short-acting anticholinergics: What is the MOA?

Block muscarninic receptors in resp. tract

32

Short-acting anticholinergics: Lipid soluble or not lipid soluble?

NOT lipid soluble

This is good and keeps the drug in the resp. tract

33

What are the adverse effects of short-acting anticholinergics?

Dry mouth, irritated throat

Since these drugs are not lipid soluble, they don't cause all anti-cholinergic effects like you would expect. These drugs are sprayed into the mouth--so you can expect the dry mouth anti-cholinergic effect to show up here with this drug

34

What is the short-acting anticholinergic drug?

Ipratropium--COPD rescue med

35

What is the long-acting anticholinergic med MOA?

Block muscarninic receptors in the resp. tract

36

Are long-acting anticholinergics controllers or rescuers?

Controllers--last for 24 hours

37

What do long-acting anticholinergics control (asthma or COPD)

COPD controller

38

What is the drug for long-acting anticholinergic control?

Tiotropium

39

Long-acting anticholinergic: Tiotropium
What is the special thing we need to know about this drug form?

It is a capsule but you put it inside a crusher thing and the capsule is punctured and you suck the drug into the lungs. DO NOT SWALLOW THE CAPSULE

40

What is the oral agent that can be given for asthma?

Montelukast

41

Is montelukast an oral agent to swallow or chew?

Chewable!!

42

What does montelukast do?

Blocks leukotrienes (inflammatory substance)

43

What side-effects occur with montelukast for most people?

None

44

There are some reports of neuropsychiatric events when taking a montelukast. This is RARE. What are the 2 examples of the neuropsychiatric events that could occur?

Mood change
Suicidal