Antidepressants: Atypical Flashcards Preview

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Flashcards in Antidepressants: Atypical Deck (13):
1

What are the 3 examples of atypical antidepressants mentioned in the class notes?

Bupropion
Mirtazapine
Trazodone

2

Which of the 3 examples is a DNRI (dopimine-norepinephrine reuptake inhibitor)?

Bupropion

3

BUPROPION: What are 4 effects seen with this drug?

Helps with mood
Doesn't help with anxiety
No sexual side-effects--> actually may increase sexual desire
No weight gain

4

Since bupropion helps increase sexual desire, bupropion is sometimes used to counteract sexual dysfunction in patients taking what other anti-depressant?

SSRIs; SSRIs have a lot of sexual side-effect complaints; giving bupropion instead may help with that

5

What is the side-effect of bupropion that is the greatest concern?

Seizures

6

Can bupropion and MAOIs be taken together?

No

7

Mirtazapine: What receptor does mirtazapine block? What does that blockage lead to?

Mirtazapine blocks histamine receptors, which promotes sedation and weight gain.

8

How much weight gain may be seen in patients taking mirtazapine?

40-60 lbs

9

Can you take mirtazapine with MAOIs?

No

10

Why might HIV patients be prescribed mirtazapine?

Because HIV patients may have muscle wasting--> Mirtazapine causes weight gain, so in HIV patients, weight gain is actually a beneficial and desired side-effect

11

Trazadone: MOA?

Trazadone produces selective, but moderate, blocked of serotonin uptake

12

What is trazadone usually prescribed for?

A sleep-aid

13

What are the benefits in trazadone?

Sleep-aid that doesn't affect REM sleep
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