Flashcards in Antidepressants: Atypical Deck (13):
1
What are the 3 examples of atypical antidepressants mentioned in the class notes?
Bupropion
Mirtazapine
Trazodone
2
Which of the 3 examples is a DNRI (dopimine-norepinephrine reuptake inhibitor)?
Bupropion
3
BUPROPION: What are 4 effects seen with this drug?
Helps with mood
Doesn't help with anxiety
No sexual side-effects--> actually may increase sexual desire
No weight gain
4
Since bupropion helps increase sexual desire, bupropion is sometimes used to counteract sexual dysfunction in patients taking what other anti-depressant?
SSRIs; SSRIs have a lot of sexual side-effect complaints; giving bupropion instead may help with that
5
What is the side-effect of bupropion that is the greatest concern?
Seizures
6
Can bupropion and MAOIs be taken together?
No
7
Mirtazapine: What receptor does mirtazapine block? What does that blockage lead to?
Mirtazapine blocks histamine receptors, which promotes sedation and weight gain.
8
How much weight gain may be seen in patients taking mirtazapine?
40-60 lbs
9
Can you take mirtazapine with MAOIs?
No
10
Why might HIV patients be prescribed mirtazapine?
Because HIV patients may have muscle wasting--> Mirtazapine causes weight gain, so in HIV patients, weight gain is actually a beneficial and desired side-effect
11
Trazadone: MOA?
Trazadone produces selective, but moderate, blocked of serotonin uptake
12
What is trazadone usually prescribed for?
A sleep-aid
13