Test 2. 13 liver 2 Flashcards
(40 cards)
Peritoneal-pericardial diaphragmatic hernia (PPDH)
biliary cyst
congenital biliary cyst
green and yellow filled with bile
amyloidosis deposits — material in the — and causes atrophy of —
eosinophilic material
space of Disse
hepatocytes and dilation of the sinusoids
— can be associated with inflammatory conditions in other organ systems
amyloidosis
Amyloid proteins are abnormal proteins the body cannot break down and recycle as it does with normal proteins
breed predisposition for amyloidosis
Chinese Shar-pei dogs and Abyssinian, Siamese, other oriental breeds)
what can happen when you biopsy amyloid liver
Spontaneous or biopsy-induced liver rupture with hemorrhage and hemoabdomen
amyloid is stained with Lugol’s and appears
blue to black
how common are Portosystemic shunts/vascular anomalies
common
how common are infarcts in the liver?
rare
many different blood supply from portal vein and hepatic artery
how common is Peliosis hepatis (telangiectasia)
incidental vascular anomaly in the liver
R sided heart failure will do what to the liver
passive congestion
chronic will cause necrosis of the central vein
liver
chronic passive congestion
decrease in oxygen causes necrosis and fibrosis around the central vein
nutmeg liver
porto systemic shunt
Intrahepatic portosystemic shunts more frequently found in — breed dogs
large
patent ductus venosus
Extrahepatic portocaval and portoazygous shunts more frequent in — breed dogs
small
cats and ferrets
leads to hepatic hypoplasia/microhepatica
— shunts leads to hepatic hypoplasia/microhepatica
Extrahepatic portocaval and portoazygous shunts
liver is depenent on growth factors from the GI tract to grow to full size without them it will be small- hypoplasia
what does portosystemic shunt do to liver
leads to hepatic hypoplasia/microhepatica
The liver is dependent on growth factors from the GI tract including
epithelial growth factor (EGF), hepatic growth factor (HGF), insulin like growth factor (IGF), amino acids, and hormones from the pancreas (insulin and glucagon)
histo of portosystemic shunt
small lobules. Hepatic arteriolar hyperplasia
(compensatory) and bile duct hyperplasia (bystander effect)
portocaval shunt
see how small the liver is
liver secondary to cirrhosis
acquired(secondary) shunt associated with cirrhosis
— shunt liver is small because of lack of growth factors. — shunt liver is small secondary to primary hepatic disease that causes fibrosis
congenital portosystemic shunt
secondary (acquired) shunt
Primary portal vein hypoplasia is caused by
portal veins ending prematurely
can effect lobe or entire liver
can be asymptomatic with
enzyme or bile acid elevations to severe
signs associated with portal hypertension
signs of primary portal vein hypoplasia
asymptomatic with
enzyme or bile acid elevations to severe
signs associated with portal hypertension