The 15 Tenets of Inflammation Flashcards Preview

Pathology -- Gen Path > The 15 Tenets of Inflammation > Flashcards

Flashcards in The 15 Tenets of Inflammation Deck (10):
1

vessels primarily affected by inflammation?

Arterioles (Vasodilation)
Post capillary venules (Vascular permeability and cell emigration)

2

5 cardinal signs of inflammation?

Reddness, Swelling, Heat, Pain, Loss of Fxn

3

Cells primarily involved in the initiation/early phases are...

Endothelial and Mast Cells

4

Mast cells release early mediators in response to...

Trauma, Cold, Complement, IgE

5

When fluid alone passes through a vessel, you have a....

transudate
Doesn't require increase in vascular permeability

6

When fluid + proteins + cells pass through a vessel you have...

exudate
Requires increased vascular permeability

7

Neutrophils die off within...

48-72 hours

8

Macrophage response begins after...

24 hours

9

First mediators of inflammation (list a couple) are replaced by ones from macrophages (list a couple)

1st -- Histamine and Kinins
2nd -- cytokines and prostaglandins

10

How does inflamm. get turned off?

Most mediators are only short lived and acute phase proteins supply anti-inflammatory signals and neutralization of inflamm. mediators.